Zhou Huichang, Xu Yunxian, Chen Lishan, Yuan Jiajian, Guan Zhiyong, Liang Peng
The First People's Hospital of Foshan, Guangdong, China.
Front Neurol. 2024 Jul 12;15:1412959. doi: 10.3389/fneur.2024.1412959. eCollection 2024.
Language delay cannot be ignored, and there is an urgent need to determine therapies that elicit better results in a short period. However, whether transcranial direct current stimulation (tDCS) alone or in combination with other therapies can promote recovery of language and cognitive function in children with language delay remains unknown. This study aims to explore the effects of tDCS combined with language-cognitive training and home-based rehabilitation on language and cognitive ability in children with language delay.
Children with language delay who visited the Department of rehabilitation medicine or the pediatric outpatient clinic of the First People's Hospital of Foshan from January 2019 to December 2021, totaling 190 in number, were included and randomly divided into 4 groups, i.e., the family guidance group, the tDCS group, the language-cognitive training group, and the comprehensive training group. The family guidance group (47 cases) received home training. The tDCS group (46 cases) received home training and tDCS treatment. The language- cognitive training group (49 cases) adopted home training and language-cognitive training. The comprehensive training group (48 cases) took home training, language-cognitive training, and tDCS treatment. All groups received training 5 times a week for 4 weeks. The Sign-significant relations (S-S) test was applied to evaluate the language comprehension, language expression, basic learning ability, and attitude of communication of the children.
The language-cognitive training group and the comprehensive training group showed improvement after treatment ( < 0.05) regarding basic learning ability. The communication attitude of the four groups improved after intervention ( < 0.05). Particularly, the comprehensive training group had maximum improvement after intervention. No serious adverse reactions such as epilepsy, headache, and behavioral abnormalities were found.
tDCS combined with language-cognitive training and home training can improve language and cognitive ability in children with language delay.
语言发育迟缓不容忽视，迫切需要确定能在短期内取得更好效果的治疗方法。然而，经颅直流电刺激（tDCS）单独使用或与其他疗法联合使用是否能促进语言发育迟缓儿童的语言和认知功能恢复仍不清楚。本研究旨在探讨tDCS联合语言认知训练及家庭康复对语言发育迟缓儿童语言和认知能力的影响。
纳入2019年1月至2021年12月期间到佛山市第一人民医院康复医学科或儿科门诊就诊的语言发育迟缓儿童，共190例，随机分为4组，即家庭指导组、tDCS组、语言认知训练组和综合训练组。家庭指导组（47例）接受家庭训练。tDCS组（46例）接受家庭训练和tDCS治疗。语言认知训练组（49例）采用家庭训练和语言认知训练。综合训练组（48例）进行家庭训练、语言认知训练和tDCS治疗。所有组每周训练5次，共4周。采用符号-意义关系（S-S）测试评估儿童的语言理解、语言表达、基本学习能力和沟通态度。
语言认知训练组和综合训练组治疗后基本学习能力有所提高（<0.05）。干预后四组的沟通态度均有所改善（<0.05）。特别是，综合训练组干预后的改善最大。未发现癫痫、头痛和行为异常等严重不良反应。
tDCS联合语言认知训练及家庭训练可提高语言发育迟缓儿童的语言和认知能力。
