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结直肠癌早期检测中的障碍及探索潜在解决方案。

Barriers in early detection of colorectal cancer and exploring potential solutions.

作者信息

Aleissa Maryam, Drelichman Ernesto Raul, Mittal Vijay K, Bhullar Jasneet Singh

机构信息

Department of Surgery, Ascension Providence Hospital, Michigan State University College of Human Medicine, Southfield, MI 48075, United States.

College of Medicine, Princess Norah University Hospital, Riyadh 11564, Saudi Arabia.

出版信息

World J Clin Oncol. 2024 Jul 24;15(7):811-817. doi: 10.5306/wjco.v15.i7.811.

Abstract

This editorial discusses the literature review article by Tonini and Zanni, the paper was published in January 2024, and the authors provided very interesting conclusions regarding existing barriers to the early diagnosis of colon cancer. Many cancers do not have identifiable precursors, or there are currently no screening tests to find them. Therefore, these cancers do not have preventive screening options. Early detection is crucial for reducing mortality rates by identifying cancer at an earlier stage through screening, as opposed to no screening. Colorectal cancer develops from precancerous lesions, which can be detected early and potentially prevented and cured. Early detection leads to improved survival rates, decreased complications, and reduced healthcare expenses. This editorial provides a brief description of the biology of colon cancer, emphasizing the contrast in outcomes between early detection and late detection. We also describe screening programs around the globe and examine the barriers in each program. Finally, we explore potential future solutions to enhance inclusion in screening programs and improve patient compliance.

摘要

这篇社论讨论了托尼尼和赞尼发表于2024年1月的文献综述文章,作者就结肠癌早期诊断的现有障碍给出了非常有趣的结论。许多癌症没有可识别的前驱病变,或者目前没有筛查测试来发现它们。因此,这些癌症没有预防性筛查选项。早期检测对于通过筛查在更早阶段发现癌症从而降低死亡率至关重要,这与不进行筛查形成对比。结直肠癌由癌前病变发展而来,这些病变可以早期检测到,并有可能预防和治愈。早期检测可提高生存率、减少并发症并降低医疗费用。这篇社论简要描述了结肠癌的生物学特性,强调了早期检测和晚期检测在结果上的对比。我们还介绍了全球各地的筛查项目,并审视了每个项目中的障碍。最后,我们探索未来可能的解决方案,以提高筛查项目的参与度并改善患者的依从性。

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Colorectal cancer statistics, 2023.2023 年结直肠癌统计数据。
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Barriers and recommendations for colorectal cancer screening in Africa.非洲结直肠癌筛查的障碍和建议。
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