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病例报告:一只患有难产的法国斗牛犬妊娠相关免疫性血小板减少症的管理。

Case report: Management of pregnancy-associated immune thrombocytopenia in a French bulldog with dystocia.

作者信息

Feldman Rose, Bracker Kiko, Whelan Megan

机构信息

MSPCA-Angell Animal Medical Center, Boston, MA, United States.

出版信息

Front Vet Sci. 2024 Jul 12;11:1404337. doi: 10.3389/fvets.2024.1404337. eCollection 2024.

Abstract

INTRODUCTION

The objective of this case report is to describe diagnosis and management of life-threatening immune thrombocytopenia (ITP) secondary to pregnancy in a dog with concurrent dystocia.

CASE SUMMARY

A 1-year 11-month old female intact French bulldog was referred for management of severe thrombocytopenia and spontaneous hemorrhage during whelping. The thrombocytopenia was progressive from approximately 32 days of gestation. In the absence of an identifiable cause for the thrombocytopenia, the patient was treated for ITP with immunosuppressive therapies and blood and plasma transfusions. The patient was also supported through dystocia until the platelet count normalized so a Caesarean section and ovariohysterectomy (OVH) could be performed.

DISCUSSION

This is the first report documenting ITP in a whelping canine. Pregnancy is a known trigger and can affect the clinical course of autoimmune diseases in women, including ITP. It is suspected that this patient's pregnancy triggered ITP, paralleling what occurs in women.

摘要

引言

本病例报告的目的是描述一只并发难产的犬妊娠继发危及生命的免疫性血小板减少症(ITP)的诊断和管理。

病例摘要

一只1岁11个月大的未绝育法国斗牛犬因分娩时严重血小板减少和自发性出血被转诊治疗。血小板减少症从妊娠约32天时开始进展。在没有可识别的血小板减少病因的情况下,患者接受了免疫抑制治疗以及输血和血浆治疗以治疗ITP。患者在难产期间也得到了支持,直到血小板计数恢复正常,以便能够进行剖腹产和卵巢子宫切除术(OVH)。

讨论

这是第一份记录分娩期犬ITP的报告。妊娠是一个已知的触发因素,可影响包括ITP在内的女性自身免疫性疾病的临床病程。怀疑该患者的妊娠引发了ITP,这与女性的情况相似。

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