Ozdemir Levent A, Apple Andrew E, Barnes C Lowry, Stronach Benjamin, Mears Simon C, Stambough Jeffrey B
Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Department of Orthopaedic Surgery, Tulane University, New Orleans, LA, USA.
Arthroplast Today. 2024 Jun 27;27:101329. doi: 10.1016/j.artd.2024.101329. eCollection 2024 Jun.
Semipermanent functional spacers are now utilized for prosthetic joint infection in an attempt to avoid another surgery with 2-stage treatment. This study evaluates the results of metal-on-polyethylene articulating spacers for the treatment of chronic native septic knee arthritis.
This is a retrospective review of 18 patients treated with metal-on-polyethylene articulating antibiotic spacers constructed with all-polyethylene tibial components or with polyethylene inserts (PIs) with Steinmann pins or screws for chronic native knee infection. Demographic information, spacer construct type, prior knee surgery, complications, infecting organisms, infection eradication, and functional results were analyzed.
Of 18, 8 (44%) spacers were all-polyethylene tibial components and 10 (56%) were PI. Of 18 patients, 5 (28%) experienced spacer complications. Of 18 patients, 12 (67%) underwent a second reimplantation surgery (mean 106 days), while 6 (33%) retained their spacer (average duration 425 days). The PI group performed better in Knee Injury and Osteoarthritis Outcome score for Joint Replacement according to minimum clinically important difference and patient acceptable symptom state (PASS) criteria. The overall reimplantation group achieved Knee Injury and Osteoarthritis Outcome score for Joint Replacement PASS criteria and minimum clinically important difference criteria, while the maintained articulating spacer group did not achieve PASS criteria; however, they did reach minimum clinically important difference.
Functional articulating spacers are a viable treatment for chronic, native knee septic arthritis. The PI patient group had a greater improvement in Knee Injury and Osteoarthritis Outcome score for Joint Replacement scores and had no significant difference in reimplantation rate as the all-polyethylene tibial components patient group. Both planned 2-stage reimplantation and longer-term spacer retention show promising results for this difficult clinical problem.
目前,半永久性功能性间隔物被用于治疗人工关节感染,以避免两阶段治疗中的再次手术。本研究评估金属对聚乙烯关节成形间隔物治疗慢性原发性化脓性膝关节炎的效果。
这是一项对18例患者的回顾性研究,这些患者接受了金属对聚乙烯关节成形抗生素间隔物治疗,该间隔物由全聚乙烯胫骨部件或带有斯氏针或螺钉的聚乙烯衬垫(PI)构成,用于治疗慢性原发性膝关节感染。分析了人口统计学信息、间隔物结构类型、既往膝关节手术、并发症、感染微生物、感染根除情况及功能结果。
18个间隔物中,8个(44%)是全聚乙烯胫骨部件,10个(56%)是PI。18例患者中,5例(28%)出现间隔物并发症。18例患者中,12例(67%)接受了第二次再植入手术(平均106天),而6例(33%)保留了间隔物(平均持续时间425天)。根据最小临床重要差异和患者可接受症状状态(PASS)标准,PI组在关节置换的膝关节损伤和骨关节炎结局评分方面表现更好。总体再植入组达到了关节置换PASS标准和最小临床重要差异标准,而保留关节成形间隔物组未达到PASS标准;然而,他们确实达到了最小临床重要差异。
功能性关节成形间隔物是治疗慢性原发性膝关节化脓性关节炎的一种可行方法。PI患者组在关节置换的膝关节损伤和骨关节炎结局评分方面有更大改善,且再植入率与全聚乙烯胫骨部件患者组无显著差异。计划性两阶段再植入和长期间隔物保留对这一棘手的临床问题均显示出有前景的结果。