[Immunostimulating activity of combined antigens of Klebsiella pneumoniae, Staphylococcus, Proteus and Escherichia coli and separate components in cross infection].

Experiments on mice have revealed that the combined preparation of K. pneumoniae, Staphylococcus, Proteus and E. coli antigens possesses pronounced immunostimulating activity against the microorganisms whose antigens make up this combined preparation, as well as against Haemophilus influenzae, type b. Cross protection between the antigens making up the preparation was observed, as well as of each of its components with respect to H. influenzae, type b. The activity of the combined antigenic preparation has been shown to exceed that of its monocomponents, as manifested under the conditions of cross infection. These experimental data may serve as a prerequisite for the development of an immunostimulant for the treatment of patients with chronic pyoinflammatory diseases.