BOADICEA模型：60岁及以上女性乳腺癌风险的更新
BOADICEA model: updates to the breast cancer risks for ages 60 years and older.
作者信息
Ficorella Lorenzo, Yang Xin, Easton Douglas F, Antoniou Antonis C
机构信息
Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.
出版信息
BJC Rep. 2024;2(1):53. doi: 10.1038/s44276-024-00079-1. Epub 2024 Jul 24.
Abstract
Breast cancer risks in older pathogenic variant carriers are understudied. Recent studies show a marked decline in the relative risk at older ages. We used data from two large studies to update the breast cancer risks in the BOADICEA model for carriers 60 years and older.
摘要
老年致病基因变异携带者的乳腺癌风险研究不足。近期研究表明，老年人群的相对风险显著下降。我们利用两项大型研究的数据，更新了BOADICEA模型中60岁及以上携带者的乳腺癌风险。
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