Shavlovskaya O A
International University of Restorative Medicine, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2024;124(6):43-47. doi: 10.17116/jnevro202412406143.
The article reflects the results of a number of studies that demonstrate the therapeutic effectiveness of Recognan (citicoline) in anxiety-depressive and asthenic disorders against the background of somatic and neurological diseases, in the correction of post-stroke depression. Recent experimental animal studies prove the effect of citicoline on anxiety and depression. In the complex effect, Recognan potentiates the main pharmacological effect of antidepressants and anxiolytics. In some studies, a dose-dependent change in animal behavior has been observed in response to the analgesic and antidepressant effects of citicoline. The effectiveness of citicoline in combination with transcranial direct current stimulation in the treatment of depression has been shown. The analysis of these research materials allows us to recommend Recognan in the complex therapy of asthenic and anxiety-depressive disorders in response to such pathological conditions as anxiety, asthenia, depression.
本文反映了多项研究的结果，这些研究表明，在躯体疾病和神经疾病背景下，认知能（胞磷胆碱）对焦虑抑郁和虚弱症具有治疗效果，可用于纠正中风后抑郁。近期的实验动物研究证实了胞磷胆碱对焦虑和抑郁的作用。在综合作用方面，认知能增强了抗抑郁药和抗焦虑药的主要药理作用。在一些研究中，已观察到动物行为因胞磷胆碱的镇痛和抗抑郁作用而发生剂量依赖性变化。已证明胞磷胆碱与经颅直流电刺激联合使用治疗抑郁症的有效性。对这些研究材料的分析使我们能够推荐认知能用于虚弱症以及焦虑抑郁障碍的综合治疗，以应对焦虑、虚弱、抑郁等病理状况。
