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双相障碍患者的团体心理教育:延迟复发发作和严重程度的有效性回顾性研究。

Group psychoeducation for patients with bipolar disorder: a retrospective study on effectiveness in delaying relapse episodes and intensity.

机构信息

UO Psichiatria, 1 ASST, Mantova, Italy.

出版信息

Riv Psichiatr. 2024 Jul-Aug;59(4):186-190. doi: 10.1708/4320.43059.

DOI:10.1708/4320.43059
PMID:39072609
Abstract

INTRODUCTION

Group psychoeducation is effective in preventing relapse in bipolar disorder. It's indicated as an adjunctive intervention to pharmacotherapy for all outpatients. This retrospective, single center experience of group psychoeducation for bipolar disorder over a 6 years period, aims to assess severity of symptoms and comparative relapse episodes and intensity prior to and following psychoeducation as well as evaluating the decrease in hospitalizations and days of hospitalization.

METHODS

Between 2014 and 2019 patients with a bipolar disorder were invited to attend a Colom model group psychoeducation (weekly 90 minutes sessions for 22 weeks). Depression and mania were assessed at baseline, following psychoeducation, 6 months and 12 months with the Hamilton Depression Rating Scale (HDRS) and Young Mania Rating Scale (YMRS). Patient specific hospitalization admissions data for 3 years prior to and 3 years following psychoeducation course were accessed. Subgroup analyses were performed according to patient sex and age with ANOVA methodology.

RESULTS

Of the 95 eligible patients, 77 completed psychoeducation: 18 (19%) patients dropped out. Mean patient age was 45 years and 33 (43%) were male. Overall and subgroup specific YMRS and HDRS improved significantly throughout follow-up (p<0.01). Hospitalization analyses (45 patients; 58.4%) revealed a significant decrease in relapse and hospital stay days after psychoeducation, p<0.01.

DISCUSSION

We provide evidence of applicability and efficacy of adjunctive psychoeducation in a real-world setting. Advantages observed were independent of patient sex and age. Analysis of the optimal number of sessions provided to patients according to efficacy and retention rates is required.

CONCLUSIONS

Despite inherent study design limitations, retrospective evaluation of a single-center psychoeducation program supports evidence of psychoeducation effectiveness in significantly reducing the severity of bipolar disorder and hospitalizations, despite a drop-out rate of 1 in 5.

摘要

简介

团体心理教育在预防双相情感障碍复发方面是有效的。它被作为药物治疗的辅助干预措施,适用于所有门诊患者。本研究回顾性分析了 6 年来在单一中心开展的双相情感障碍团体心理教育,旨在评估心理教育前后症状严重程度和复发情况,以及评估心理教育后住院率和住院天数的变化。

方法

在 2014 年至 2019 年间,邀请患有双相情感障碍的患者参加 Colom 模式的团体心理教育(每周 90 分钟,共 22 周)。在基线、心理教育后、6 个月和 12 个月时,使用汉密尔顿抑郁量表(HDRS)和杨氏躁狂量表(YMRS)评估抑郁和躁狂。在进行心理教育课程之前和之后的 3 年内,获取了每位患者的特定住院入院数据。采用方差分析方法,根据患者性别和年龄进行亚组分析。

结果

在 95 名符合条件的患者中,有 77 名完成了心理教育:18 名(19%)患者退出。患者平均年龄为 45 岁,33 名(43%)为男性。总体和亚组特定的 YMRS 和 HDRS 在随访过程中均显著改善(p<0.01)。住院分析(45 名患者;58.4%)显示,心理教育后复发和住院天数显著减少,p<0.01。

讨论

我们提供了在现实环境中辅助心理教育的适用性和疗效证据。观察到的优势独立于患者性别和年龄。根据疗效和保留率分析为患者提供最佳次数的课程是必要的。

结论

尽管存在研究设计的局限性,但对单中心心理教育计划的回顾性评估支持心理教育在显著减轻双相情感障碍严重程度和住院率方面的有效性,尽管有 1/5 的患者中途退出。

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