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The influence of purified somatomedins and insulin on foetal rat brain DNA synthesis in vitro.

作者信息

Enberg G, Tham A, Sara V R

出版信息

Acta Physiol Scand. 1985 Oct;125(2):305-8. doi: 10.1111/j.1748-1716.1985.tb07720.x.

DOI:10.1111/j.1748-1716.1985.tb07720.x
PMID:3907275
Abstract

The two main forms of somatomedins, termed insulin-like growth factor I and II (IGF-I and IGF-II), have been isolated from human plasma. Pure IGF-I or IGF-II was incubated with foetal rat brain cells and found to be equipotent in stimulating the [3H]thymidine incorporation into DNA, despite the fact that IGF-I not is present during foetal life.

摘要

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引用本文的文献

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Characterization of somatomedins from human fetal brain: identification of a variant form of insulin-like growth factor I.人胎儿脑生长调节素的特性：胰岛素样生长因子I变异体的鉴定。
Proc Natl Acad Sci U S A. 1986 Jul;83(13):4904-7. doi: 10.1073/pnas.83.13.4904.
2
Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system.胰岛素样生长因子II基因在成年大鼠中枢神经系统脉络丛和软脑膜中的表达。
Proc Natl Acad Sci U S A. 1988 Jan;85(1):141-5. doi: 10.1073/pnas.85.1.141.
3
Regulation of insulin-like growth factor II receptors by growth hormone and insulin in rat adipocytes.
生长激素和胰岛素对大鼠脂肪细胞中胰岛素样生长因子II受体的调节
Proc Natl Acad Sci U S A. 1987 Jun;84(11):3619-22. doi: 10.1073/pnas.84.11.3619.
4
Insulin growth factors regulate the mitotic cycle in cultured rat sympathetic neuroblasts.胰岛素生长因子调节培养的大鼠交感神经母细胞的有丝分裂周期。
Proc Natl Acad Sci U S A. 1988 Jun;85(11):4066-70. doi: 10.1073/pnas.85.11.4066.
5
Molecular biology of the insulin-like growth factors. Relevance to nervous system function.胰岛素样生长因子的分子生物学。与神经系统功能的相关性。
Mol Neurobiol. 1990 Spring-Summer;4(1-2):93-127. doi: 10.1007/BF02935586.
6
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