Krusell L, Nielsen H K, Baelum J, Lundqvist G, Omland O, Vaeth M, Husted S E, Mogensen C E, Geday E
Acta Med Scand. 1985;218(3):323-7. doi: 10.1111/j.0954-6820.1985.tb06132.x.
Chronic effects of organic solvents on renal function were measured by creatinine clearances and urinary excretion rates of beta 2-microglobulin and albumin. Forty-three male printing trade workers occupationally exposed to different organic solvents for 9-25 years were compared with 43 age-matched male controls. No differences were found either in creatinine clearances or average basal levels of beta 2-microglobulin and albumin excretion rates, whereas a positive relation could be demonstrated between alcohol consumption on the day before the trial and urinary excretion rate of albumin. This investigation did not reveal any adverse renal effects of moderate chronic exposure to organic solvents in a group of active trade workers.
通过肌酐清除率以及β2-微球蛋白和白蛋白的尿排泄率来测定有机溶剂对肾功能的慢性影响。将43名职业性接触不同有机溶剂9至25年的男性印刷行业工人与43名年龄匹配的男性对照者进行比较。在肌酐清除率或β2-微球蛋白和白蛋白排泄率的平均基础水平方面均未发现差异，然而，试验前一天的饮酒量与白蛋白尿排泄率之间呈正相关。该调查未发现一组在职行业工人中中度慢性接触有机溶剂会对肾脏产生任何不良影响。
