Cheng Fei, He Li, Deng Dachuan, Zhang Jinhui, Liu Cheng
Department of Critical Care Medicine, The Third People's Hospital of Chengdu, Chengdu, China.
Department of Critical Care Medicine, Dazhou Central Hospital, Dazhou, China.
J Asthma. 2025 Jan;62(1):45-55. doi: 10.1080/02770903.2024.2386442. Epub 2024 Aug 3.
Asthma is a common chronic respiratory disease in children. Understanding incidence and mortality trends is crucial for prevention and intervention strategies.
Data from the Global Burden of Disease (GBD) study were used to analyze asthma incidence and mortality trends among children aged 0-14 in 204 countries from 1990 to 2019. The 30-year trends were calculated using the Estimated Annual Percentage Change (EAPC).
Globally, pediatric asthma cases increased from 18,857,697 in 1990 to 20,191,786 in 2019. Incidence rates for children <5, 5-9, and 10-14 years are 1509.36, 980.25, and 586.95 per 100,000, respectively. Over 30 years, pediatric asthma mortality rates significantly decreased from 1.59 to 0.51 per 100,000, with minimal gender differences. High-income North America, Tropical Latin America, and the Caribbean show the highest incidence rates at 3203.2, 2493.83, and 2314.8 per 100,000. The USA, Puerto Rico, and Haiti have the highest national rates at 3357.17, 2695.30, and 2605.38 per 100,000. Regions with higher Sociodemographic Index levels tend to have higher incidence rates. Pediatric asthma prevalence varies by region and age group.
Our study of asthma incidence and mortality rates among children aged 0-14 across 204 countries from 1990 to 2019 reveals significant global disparities. These findings underscore the influence of socioeconomic and environmental factors on asthma prevalence and outcomes.
哮喘是儿童常见的慢性呼吸道疾病。了解发病率和死亡率趋势对于预防和干预策略至关重要。
利用全球疾病负担(GBD)研究的数据,分析1990年至2019年204个国家0至14岁儿童的哮喘发病率和死亡率趋势。使用估计年变化百分比(EAPC)计算30年趋势。
全球范围内,儿童哮喘病例从1990年的18,857,697例增加到2019年的20,191,786例。<5岁、5至9岁和10至14岁儿童的发病率分别为每10万人1509.36例、980.25例和586.95例。30多年来,儿童哮喘死亡率从每10万人1.59例显著降至0.51例,性别差异极小。高收入的北美、热带拉丁美洲和加勒比地区的发病率最高,分别为每10万人3203.2例、2493.83例和2314.8例。美国、波多黎各和海地的国家发病率最高,分别为每10万人3357.17例、2695.30例和2605.38例。社会人口指数水平较高的地区往往发病率较高。儿童哮喘患病率因地区和年龄组而异。
我们对1990年至2019年204个国家0至14岁儿童哮喘发病率和死亡率的研究揭示了显著的全球差异。这些发现强调了社会经济和环境因素对哮喘患病率和结局的影响。