Pan Roubai, Fan Qin, Tao Rong
Department of Cardiovascular Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 200025 Shanghai, China.
Rev Cardiovasc Med. 2023 Sep 5;24(9):247. doi: 10.31083/j.rcm2409247. eCollection 2023 Sep.
Depression is common among patients with acute coronary syndrome (ACS). Although multiple studies have confirmed that depression is an independent risk factor for poor outcomes in ACS, general awareness of this issue is still limited. Ongoing research has described detailed aspects of depression in ACS, with various mechanistic hypotheses put forward to explain the complexity of this comorbidity. Several investigations have explored management strategies in this subgroup of patients, including screening for depression, antidepressant treatment, and cardiac rehabilitation. However, evidence of long-term improvement in clinical outcomes is still scarce, and a more comprehensive understanding of the underlying mechanisms that link depression with ACS is required to further improve disease management.
抑郁症在急性冠状动脉综合征（ACS）患者中很常见。尽管多项研究证实抑郁症是ACS患者预后不良的独立危险因素，但对此问题的普遍认识仍然有限。正在进行的研究已经描述了ACS中抑郁症的详细情况，并提出了各种机制假说来解释这种合并症的复杂性。几项调查探讨了该亚组患者的管理策略，包括抑郁症筛查、抗抑郁治疗和心脏康复。然而，临床结局长期改善的证据仍然很少，需要更全面地了解将抑郁症与ACS联系起来的潜在机制，以进一步改善疾病管理。
