Ma Ling-Chao, Zhao Han-Qing, Wu Logan Blair, Cheng Zi-le, Liu Chang
School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
One Health Centre, Shanghai Jiao Tong University and the University of Edinburgh, Shanghai, China.
Sci One Health. 2023 Aug 25;2:100037. doi: 10.1016/j.soh.2023.100037. eCollection 2023.
The microbiome encompasses the genomes of the microorganisms that inhabit specific environments. One Health is an emerging concept, recognised as a cohesive, harmonising approach aimed at sustainably improving the well-being of humans, animals, and the environment. The microbiome plays a crucial role in the One Health domain, facilitating interactions among humans, animals, and the environment, along with co-evolution, co-development, co-metabolism, and co-regulation with their associated humans and animals. In addition, the microbiome regulates environmental health through interactions with plant microbiota, which actively participate in substance cycling (particularly the carbon and nitrogen cycles) and influence the overall energy flow in the biosphere. Moreover, antibiotic resistance genes present in microbiota can lead to widespread drug resistance in both humans and animals. This review explores the impact of the microbiome on humans, animals, and the environment, highlighting the significance of focusing on this field in One Health research.
微生物组包含栖息于特定环境中的微生物的基因组。“同一健康”是一个新兴概念，被视为一种旨在可持续地改善人类、动物和环境福祉的凝聚性、协调性方法。微生物组在“同一健康”领域发挥着关键作用，促进人类、动物和环境之间的相互作用，以及与其相关的人类和动物的共同进化、共同发展、共同代谢和共同调节。此外，微生物组通过与植物微生物群的相互作用来调节环境健康，植物微生物群积极参与物质循环（特别是碳和氮循环）并影响生物圈中的整体能量流动。此外，微生物群中存在的抗生素抗性基因可导致人类和动物中广泛的耐药性。本综述探讨了微生物组对人类、动物和环境的影响，强调了在“同一健康”研究中关注这一领域的重要性。
