Python Ndekou Paul, Drake Archie, Lomax Jake, Dione Michel, Faye Ardiouma, Njiemessa Nsangou Mohamed Daly, Korir Lilian, Sklar Elizabeth
Cheikh Anta Diop University, Dakar 10700, Senegal.
University of Lincoln, Brayford Pool, Lincoln, LN6 7TS, United Kingdom.
Sci One Health. 2023 Nov 4;2:100051. doi: 10.1016/j.soh.2023.100051. eCollection 2023.
Antimicrobial resistance (AMR) is a substantial global One Health problem. This paper reports on initial, proof-of-concept development of an agent-based model (ABM) as part of wider modelling efforts to support collaborations between groups interested in policy development for animal health and food systems. The model simulates AMR in poultry production in Senegal. It simultaneously addresses current policy issues, builds on existing modelling in the domain and describes AMR in the broiler chicken production cycle as seen by producers and veterinarians. This enables implementation and assessment of producer antimicrobial use and infection prevention and control strategies in terms of immediate economic incentives, potentially helping to advance conversations by addressing national policy priorities. Our model is presented as a flexible tool with promise for extension as part of AMR policy development in Senegal and West Africa, using participatory approaches. This work indicates that ABM can potentially play a useful role in fostering counter-AMR initiatives driven by food system actor behaviour in lower- and middle-income countries more generally.
抗菌药物耐药性（AMR）是一个重大的全球性“同一健康”问题。本文报告了基于主体模型（ABM）的初步概念验证开发情况，这是更广泛建模工作的一部分，旨在支持对动物健康和食品系统政策制定感兴趣的各方之间的合作。该模型模拟了塞内加尔家禽生产中的抗菌药物耐药性情况。它同时解决当前的政策问题，以该领域现有的建模为基础，并描述了生产者和兽医所看到的肉鸡生产周期中的抗菌药物耐药性情况。这使得能够根据直接的经济激励措施来实施和评估生产者的抗菌药物使用以及感染预防和控制策略，有可能通过解决国家政策重点来推动相关讨论。我们的模型是一个灵活的工具，有望作为塞内加尔和西非抗菌药物耐药性政策制定的一部分，采用参与式方法进行扩展。这项工作表明，基于主体模型在更广泛地促进低收入和中等收入国家由食品系统行为者行为驱动的抗抗菌药物耐药性倡议方面可能发挥有益作用。
