Cheemalapati Shashank, R Deepashree, S R Sujatha, Karthik M V S Krishna, D Narayanappa
Department of General Medicine, JSS Medical College and Hospital, Mysore, IND.
Department of Microbiology, JSS Medical College and Hospital, Mysore, IND.
Cureus. 2024 Jun 29;16(6):e63451. doi: 10.7759/cureus.63451. eCollection 2024 Jun.
Laboratories with a well-established diagnostic stewardship program for culture and the antimicrobial susceptibility test (C-AST) play a key role in guiding clinicians to institute specific targeted therapy. Blood culture is one of the most critical investigations performed at a microbiology laboratory. Therefore, it is particularly important to develop a robust diagnostic stewardship model for the blood culture laboratory division. Aiming at this hypothesis, this hospital-based clinical audit carried out within the Department of General Medicine, centered on the critical domain of antimicrobial stewardship (AMSP). The audit's primary objective was to systematically evaluate prevailing practices and pinpoint areas necessitating refinement in the administration of antimicrobial agents. Employing a meticulous approach involving exhaustive data scrutiny and feedback mechanisms, the audit unearthed strategic opportunities to optimize prescription patterns, curtail unwarranted antimicrobial utilization, and fortify adherence to established guidelines. The subsequent execution of targeted interventions, encompassing educational initiatives and routine performance feedback, culminated in a noteworthy enhancement of antimicrobial prescribing practices. These outcomes unequivocally underscore the efficacy of the audit in cultivating a milieu of judicious antimicrobial utilization, thereby augmenting patient care and mitigating antibiotic resistance within the department.
拥有完善的培养及抗菌药物敏感性试验(C-AST)诊断管理计划的实验室,在指导临床医生制定特定的靶向治疗方案方面发挥着关键作用。血培养是微生物实验室进行的最关键检查之一。因此,为血培养实验室部门建立一个强大的诊断管理模型尤为重要。基于这一假设,该以医院为基础的临床审计在普通内科开展,以抗菌药物管理(AMSP)的关键领域为中心。审计的主要目标是系统评估现行做法,并找出抗菌药物管理方面需要改进的领域。通过采用细致入微的方法,包括详尽的数据审查和反馈机制,审计发现了优化处方模式、减少不必要的抗菌药物使用以及加强对既定指南的遵守的战略机会。随后实施的有针对性的干预措施,包括教育举措和常规绩效反馈,最终显著改善了抗菌药物处方做法。这些结果明确强调了审计在营造明智使用抗菌药物环境方面的成效,从而改善了科室的患者护理并减轻了抗生素耐药性。