针对鸡神经系统中神经胶质细胞的单克隆抗体。
Monoclonal antibodies specific for glia in the chick nervous system.
作者信息
Lemmon V
出版信息
Brain Res. 1985 Nov;355(1):111-20. doi: 10.1016/0165-3806(85)90010-0.
PMID:3907748
Abstract
Two monoclonal antibodies that bind to previously undescribed glial antigens are discussed. One antibody, 3A7, binds to Müller cells in the chick retina and radial glia in the optic tectum. The other, 7G4, also binds to Müller cells, However, in the tectum it binds to a small cell type in the stratum opticum. The developmental appearance of the antigens and their localization in cells in tissue culture are also presented.
摘要
本文讨论了两种与先前未描述的神经胶质抗原结合的单克隆抗体。一种抗体3A7可与鸡视网膜中的穆勒细胞以及视顶盖中的放射状胶质细胞结合。另一种抗体7G4也能与穆勒细胞结合，不过，在视顶盖中它与视神经层中的一种小细胞类型结合。文中还介绍了这些抗原的发育表现及其在组织培养细胞中的定位。
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