WISE最新消息：对无阻塞性冠状动脉女性缺血与心力衰竭认识的贡献
Latest from the WISE: Contributions to the Understanding of Ischemia and Heart Failure among Women with No Obstructive Coronary Arteries.
作者信息
Hansen Breanna, Nelson Michael D, Handberg Eileen M, Pepine Carl J, Bairey Merz C Noel, Wei Janet
机构信息
Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Department of Kinesiology, University of Texas at Arlington, Arlington, TX 76019, USA.
出版信息
Rev Cardiovasc Med. 2023 Mar 15;24(3):90. doi: 10.31083/j.rcm2403090. eCollection 2023 Mar.
Since 1996, the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) has been investigating pathophysiological processes underlying ischemic heart disease in women and related outcomes. Recent findings have focused on women with signs and symptoms of ischemia and no obstructive coronary arteries (INOCA) and their elevated risk for heart failure with preserved ejection fraction (HFpEF). This review summarizes the latest WISE findings related to INOCA and pre-HFpEF characteristics, addressing our understanding of contributions from traditional vs nontraditional risk factors in women.
自1996年以来，美国国立心肺血液研究所资助的女性缺血综合征评估（WISE）项目一直在研究女性缺血性心脏病的病理生理过程及相关结局。最近的研究结果聚焦于有缺血症状和体征但无阻塞性冠状动脉病变（INOCA）的女性，以及她们发生射血分数保留的心力衰竭（HFpEF）的风险升高情况。本综述总结了WISE关于INOCA和HFpEF前期特征的最新研究结果，阐述了我们对女性传统和非传统危险因素作用的理解。
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