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酒精对心脏的有害影响:高血压和心肌病。

Detrimental Effects of Alcohol on the Heart: Hypertension and Cardiomyopathy.

作者信息

Figueredo Vincent M, Patel Akash

机构信息

Department of Cardiology, St Mary Medical Center, Langhorne, PA 19047, USA.

出版信息

Rev Cardiovasc Med. 2023 Oct 17;24(10):292. doi: 10.31083/j.rcm2410292. eCollection 2023 Oct.

DOI:10.31083/j.rcm2410292
PMID:39077572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11273158/
Abstract

BACKGROUND

Epidemiological evidence suggests a J-shaped association between alcohol consumption and cardiovascular mortality, with higher cardiovascular event rates occurring among abstainers and heavy drinkers compared to moderate consumers. However, this hypothesis has been challenged by more recent studies. Furthermore, ethnicity, gender, type of alcoholic beverage, and pattern of alcohol intake, influence the relationship between alcohol and heart health.

METHODS

We undertook a review of the relavent literature utilizing PubMed.

RESULTS

Heavy alcohol consumption causes resistant hypertension, cardiomyopathy, arrhythmias, hemorrhagic strokes, as well as hepatic cirrhosis and pancreatitis. Excessive drinking is the third most preventable cause of death worldwide behind hypertension and smoking.

CONCLUSIONS

In this review, we discuss the effects of alcohol abuse on hypertension (a major cause of myocardial infarction and stroke) and alcoholic cardiomyopathy. Another article in this Special Issue "Alcohol and Heart Health" discusses the problem with alcohol and arrhythmias sudden cardiac death.

摘要

背景

流行病学证据表明,酒精消费与心血管死亡率之间呈J形关联,与适度饮酒者相比,戒酒者和重度饮酒者的心血管事件发生率更高。然而,这一假设受到了最近研究的挑战。此外,种族、性别、酒精饮料类型和饮酒模式会影响酒精与心脏健康之间的关系。

方法

我们利用PubMed对相关文献进行了综述。

结果

大量饮酒会导致顽固性高血压、心肌病、心律失常、出血性中风,以及肝硬化和胰腺炎。过量饮酒是全球第三大可预防的死亡原因,仅次于高血压和吸烟。

结论

在本综述中,我们讨论了酒精滥用对高血压(心肌梗死和中风的主要原因)和酒精性心肌病的影响。本期特刊“酒精与心脏健康”中的另一篇文章讨论了酒精与心律失常及心源性猝死的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea28/11273158/c332544dc847/2153-8174-24-10-292-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea28/11273158/c332544dc847/2153-8174-24-10-292-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea28/11273158/c332544dc847/2153-8174-24-10-292-g1.jpg

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Korean J Intern Med. 2020 Jul;35(4):906-916. doi: 10.3904/kjim.2019.016. Epub 2019 Dec 6.
3
Association between alcohol intake and incident hypertension in the Korean population.
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Alcohol. 2019 Jun;77:19-25. doi: 10.1016/j.alcohol.2018.09.002. Epub 2018 Sep 18.
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Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.2016 年全球疾病负担研究:1990 年至 2016 年 195 个国家和地区的酒精使用和负担:系统分析。
Lancet. 2018 Sep 22;392(10152):1015-1035. doi: 10.1016/S0140-6736(18)31310-2. Epub 2018 Aug 23.
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J Am Heart Assoc. 2018 Jun 27;7(13):e008202. doi: 10.1161/JAHA.117.008202.
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