Yu Ga-In, Yang Pil-Sung, Kim Moon-Hyun, Jin Moo-Nyun, Jang Eunsun, Yu Hee Tae, Kim Tae-Hoon, Pak Hui-Nam, Lee Moon-Hyoung, Joung Boyoung
Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, 03722 Seoul, Republic of Korea.
Division of Cardiology, CHA Bundang Medical Center, CHA University, 13497 Seongnam, Republic of Korea.
Rev Cardiovasc Med. 2022 Apr 26;23(5):153. doi: 10.31083/j.rcm2305153. eCollection 2022 May.
Regular exercise improves the functional ability and quality of life of patients with heart failure (HF). However, studies on the results of intensity of exercise in the older population are scarce, especially in the Asian population.
A total of 8982 older people (age 65 years) with HF were selected from the Korean National Health Insurance Service-Senior database (2005-2012). Participants were stratified according to the levels of physical activity per week as follows: (1) inactive group; (2) insufficiently active group: 1-499 metabolic equivalent task minutes (MET-min)/week; (3) active group: 500-999 MET-min/week; and (4) highly active group: 1000 MET-min/week. During a median follow-up period of 3.2 years, the incidence and risk of mortality were reduced in the insufficiently active (6.7 vs. 4.2 per 100 person-years, adjusted hazard ratio [HR], 0.82; 95% confidence interval [CI], 0.71-0.94; 0.001), active (3.8 per 100 person-years; HR, 0.81; 95% CI, 0.70-0.95; = 0.010), and highly active (2.4 per 100 person-years; HR, 0.52; 95% CI, 0.41-0.67; 0.001) groups compared to inactive patients.
In older Asians with HF, increased physical activity reduced the risk of all-cause mortality. The mortality-reducing benefit started at a lower physical activity compared to the World Health Organization guideline (500-999 MET-min/week), and the risk decreased with more physical activity.
规律运动可改善心力衰竭（HF）患者的功能能力和生活质量。然而，关于老年人群运动强度结果的研究较少，尤其是在亚洲人群中。
从韩国国民健康保险服务-老年人数据库（2005 - 2012年）中选取了8982名65岁及以上患有HF的老年人。参与者根据每周身体活动水平分层如下：（1）不活动组；（2）活动不足组：每周1 - 499代谢当量任务分钟（MET - min）；（3）活动组：每周500 - 999 MET - min；（4）高度活动组：每周≥1000 MET - min。在中位随访期3.2年期间，活动不足组（每100人年6.7例 vs. 4.2例，调整后风险比[HR]，0.82；95%置信区间[CI]，0.71 - 0.94；P = 0.001）、活动组（每100人年3.8例；HR，0.81；95% CI，0.70 - 0.95；P = 0.010）和高度活动组（每100人年2.4例；HR，0.52；95% CI，0.41 - 0.67；P = 0.001）的死亡发生率和风险均低于不活动患者。
在患有HF的亚洲老年人中，增加身体活动可降低全因死亡率风险。与世界卫生组织指南（每周500 - 999 MET - min）相比，较低的身体活动水平即可开始获得降低死亡率的益处，且身体活动越多，风险越低。
