Ehsanipur Fahimeh, Ebrahimi Pouya, Tahernia Leila, Vafaee-Shahi Mohammad
Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Faculty of Medicine Iran University of Medical Sciences Tehran Iran.
Cardiovascular Disease Research Institute, Tehran Heart Center Tehran University of Medical Sciences Tehran Iran.
Clin Case Rep. 2024 Jul 28;12(8):e9222. doi: 10.1002/ccr3.9222. eCollection 2024 Aug.
Necrotizing pneumonia (NP) is the destruction of the interstitial part of the lung due to severe infection. One cause of this rare and fatal condition in pediatrics is Acinetobacter. Severe infections, especially pneumonia, can prone pediatric patients to ischemic stroke. This study reports an 8-year-old girl presented to the emergency department complaining of shortness of breath, fever, and fatigue. She was admitted to the intensive care unit due to respiratory distress and pericardial effusion. Swab and respiratory secretion tests for COVID-19 and Acinetobacter were positive. In her admission course, her condition deteriorated, and on the fifth day, she underwent a craniotomy due to the signs of increased intracranial pressure (ICP). The computed tomography (CT) scan showed an ischemic stroke. Despite all efforts and medical efforts, the patient's clinical condition got worse, and she died 10 days after the surgery. COVID-19 can lead to vulnerability to severe bacterial infections such as NP in pediatrics. Severe infections are a significant risk factor for ischemic stroke. The presentation might be different in intubated unconscious patients, such as detecting increased ICP signs. In severe and extensive cases of NP and ischemia, the destruction of the lungs and brain tissue might be irreversible and even lethal. Doctors and parents should consider neurologic complaints in children with infectious diseases as a serious issue since infections make children vulnerable to complications such as stroke.
坏死性肺炎(NP)是由于严重感染导致肺间质部分的破坏。儿科这种罕见且致命病症的一个病因是不动杆菌。严重感染,尤其是肺炎,会使儿科患者易患缺血性中风。本研究报告了一名8岁女孩因呼吸急促、发热和疲劳就诊于急诊科。她因呼吸窘迫和心包积液被收入重症监护病房。新冠病毒和不动杆菌的拭子及呼吸道分泌物检测呈阳性。在她的住院过程中,病情恶化,在第五天,由于颅内压(ICP)升高的迹象,她接受了开颅手术。计算机断层扫描(CT)显示为缺血性中风。尽管竭尽全力进行医疗救治,但患者的临床状况仍恶化,术后10天死亡。新冠病毒可导致儿科患者易患如NP等严重细菌感染。严重感染是缺血性中风的一个重要危险因素。对于插管无意识患者,表现可能不同,例如检测到ICP升高的迹象。在NP和缺血的严重且广泛病例中,肺和脑组织的破坏可能是不可逆的,甚至是致命的。医生和家长应将患有传染病儿童的神经学主诉视为严重问题,因为感染会使儿童易患如中风等并发症。