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自闭症青少年和成年人中,心理健康在抑郁与自伤想法关系中的潜在调节作用研究:一项为期两年的纵向研究

Examination of the Potential Moderating Role of Psychological Wellbeing in the Relationship Between Depression and Thoughts of Self-Harm in Autistic Adolescents and Adults: A Two-Year Longitudinal Study.

作者信息

Hedley Darren, Uljarević Mirko, Bury Simon M, Haschek Alexandra, Richdale Amanda L, Trollor Julian N, Stokes Mark A

机构信息

Olga Tennison Autism Research Centre, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.

Stanford University, Stanford, CA, United States of America.

出版信息

J Autism Dev Disord. 2024 Jul 30. doi: 10.1007/s10803-024-06489-x.

Abstract

PURPOSE

Autistic people have a significantly increased risk of death by suicide relative to the general population. In non-autistic samples, psychological wellbeing has been shown to moderate the relationship between depression and suicidal thoughts and behavior. Thoughts of self-harm may provide a useful indicator of suicidal risk. In this longitudinal study we examined (a) the potential role for psychological wellbeing to moderate the relationship between depressive symptoms and thoughts of self-harm and (b) the contribution of autistic traits to thoughts of self-harm.

METHODS

Participants were 209 autistic adolescents and adults aged 15 to 80 years (M = 34.20, SD = 15.38 years).

RESULTS

At both baseline and 2-year follow-up, 35% of participants reported recent thoughts of self-harm. Wellbeing was associated with autistic traits (r = - .350 to - 0.404) and depression (r = - .480 to - 0.759). Thoughts of self-harm were positively associated with autistic traits and depression (r = .242 to 0.659), and negatively associated with wellbeing (r = - .287 to - 0.609). Controlling for baseline thoughts of self-harm, depression (β = 0.254, p = .001) and autistic traits (β = 0.162, p = .007) significantly predicted thoughts of self-harm at 2-year follow-up.

CONCLUSION

Despite a lack of support for the hypothesis that wellbeing would moderate the relationship between depression and thoughts of self-harm, correlational data demonstrated significant associations between wellbeing and both depression and thoughts of self-harm. Future research considering psychological wellbeing as a potential protective factor for self-harm in autistic people is warranted.

摘要

目的

相对于普通人群,自闭症患者自杀死亡风险显著增加。在非自闭症样本中,心理健康已被证明可调节抑郁与自杀念头及行为之间的关系。自我伤害念头可能是自杀风险的一个有用指标。在这项纵向研究中,我们考察了:(a)心理健康调节抑郁症状与自我伤害念头之间关系的潜在作用;(b)自闭症特质对自我伤害念头的影响。

方法

参与者为209名年龄在15至80岁之间的自闭症青少年及成年人(M = 34.20,SD = 15.38岁)。

结果

在基线期和2年随访期,35%的参与者报告近期有自我伤害念头。心理健康与自闭症特质(r = -0.350至-0.404)及抑郁(r = -0.480至-0.759)相关。自我伤害念头与自闭症特质及抑郁呈正相关(r = 0.242至0.659),与心理健康呈负相关(r = -0.287至-0.609)。在控制基线期自我伤害念头后,抑郁(β = 0.254,p = 0.001)和自闭症特质(β = 0.162,p = 0.007)在2年随访期显著预测自我伤害念头。

结论

尽管未找到支持心理健康会调节抑郁与自我伤害念头之间关系这一假设的证据,但相关数据表明心理健康与抑郁及自我伤害念头之间存在显著关联。有必要开展未来研究,将心理健康视为自闭症患者自我伤害的潜在保护因素。

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