Azegami Tatsuhiko, Kaneko Hidehiro, Minegishi Shintaro, Suzuki Yuta, Morita Hiroyuki, Fujiu Katsuhito, Takeda Norihiko, Yokoo Takashi, Yano Yuichiro, Hayashi Kaori, Nishiyama Akira, Node Koichi
Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
Am J Hypertens. 2024 Dec 16;38(1):1-6. doi: 10.1093/ajh/hpae099.
Hypertension and cancer are both increasing with age. Recently, the new concept of "Onco-Hypertension" has been proposed to address the mutual risks posed by hypertension and cancer and to provide comprehensive care for patients with these two conditions in an aging society.
In this review, we provide an overview of the current status and future perspective of the "Onco-Hypertension," including our research findings.
Hypertension and cancer share common risk factors and may be interrelated in pathogenesis: Hypertension is involved in the development of certain cancers, and cancer survivors have a higher incidence of hypertension. With recent advances in cancer therapy, the number of cancer survivors has increased. Cancer survivors not only have a higher risk of incident hypertension but also an increased risk of future cardiovascular events, highlighting the growing importance of comprehensive care.
There exists a diverse array of epidemiological and pathophysiological relationships between hypertension and cancer. It is imperative to move the emerging scientific field of "Onco-Hypertension" forward through relentless research efforts.
高血压和癌症的发病率均随年龄增长而上升。最近，“肿瘤高血压”这一新概念被提出，以应对高血压和癌症带来的相互风险，并为老龄化社会中患有这两种疾病的患者提供全面护理。
在本综述中，我们概述了“肿瘤高血压”的现状和未来前景，包括我们的研究结果。
高血压和癌症有共同的风险因素，且在发病机制上可能相互关联：高血压参与某些癌症的发生发展，癌症幸存者患高血压的几率更高。随着癌症治疗的最新进展，癌症幸存者的数量有所增加。癌症幸存者不仅发生高血压的风险更高，未来发生心血管事件的风险也增加，这凸显了全面护理的重要性日益增加。
高血压和癌症之间存在多种流行病学和病理生理学关系。必须通过不懈的研究努力推动新兴的“肿瘤高血压”科学领域向前发展。
