O'Driscoll B R, Milburn H J, Kemeny D M, Cochrane G M, Panayi G S
Clin Allergy. 1985 Nov;15(6):547-53. doi: 10.1111/j.1365-2222.1985.tb02308.x.
The prevalence of rheumatoid arthritis (RA) was studied among 266 atopic patients attending an allergy clinic. Two patients had definite RA, a prevalence similar to that seen in the general population. We also studied the prevalence of atopy (positive skin-prick tests) and diseases associated with atopy among forty patients with RA and forty age- and sex-matched controls. The two groups had a similar prevalence of atopy (5 RA patients, nine controls) and atopic diseases (fourteen RA patients, fourteen controls) and they did not differ with respect to blood eosinophil counts or total serum IgE. Positive RAST tests to inhaled allergens were found in three RA patients and five controls and all patients had negative RAST tests to milk and egg. It was concluded that patients with rheumatoid arthritis have a normal prevalence of atopy and atopic diseases and we found no evidence that allergic factors contributed to the arthritis of the forty RA patients in the study.
在一家过敏诊所就诊的266名特应性患者中对类风湿关节炎（RA）的患病率进行了研究。两名患者患有确诊的RA，其患病率与普通人群相似。我们还在40名RA患者以及40名年龄和性别匹配的对照中研究了特应性（皮肤点刺试验阳性）的患病率以及与特应性相关的疾病。两组的特应性患病率（5名RA患者，9名对照）和特应性疾病患病率（14名RA患者，14名对照）相似，并且在血液嗜酸性粒细胞计数或总血清IgE方面没有差异。在3名RA患者和5名对照中发现对吸入性变应原的RAST试验呈阳性，并且所有患者对牛奶和鸡蛋的RAST试验均为阴性。得出的结论是，类风湿关节炎患者的特应性和特应性疾病患病率正常，并且我们没有发现证据表明过敏因素导致了该研究中40名RA患者的关节炎。
