Pistolesi M, Miniati M, Milne E N, Giuntini C
Clin Chest Med. 1985 Sep;6(3):315-44.
It has been shown that the chest roentgenogram is a sensitive and accurate pool for detecting and quantitating cardiogenic pulmonary edema. This can be done at the interstitial stage, when it cannot be detected by physical examination. At the same time the chest film can provide useful information about the circulating blood volume. In patients with the ARDS, a characteristic peripheral and patchy distribution of alveolar edema associated with an absence of peribronchial cuffing, septal lines and effusions has been shown. Enlargement of the right side of the heart and main pulmonary artery may precede actual development of edema in ARDS and provide the opportunity for early diagnosis. Radiographic "scoring" in cases of ARDS correlates well with PO2 (measured with an F1O2 = .21) standardized to a PCO2 of 40 mm Hg. The three main forms of lung edema (that is, cardiogenic, renal or overhydration, and injury edema) appear to have radiographic features that can be used to separate them. The accuracy and objectivity of this approach has been confirmed by taking the radiographic signs as input variables for discriminant analysis. Different hemodynamic conditions and changes of the extravascular protein osmotic forces may be the main factors underlying the radiographic patterns in the various types of pulmonary edema.
已经表明,胸部X线片是检测和定量心源性肺水肿的敏感且准确的手段。这在间质性阶段即可做到,而此时体格检查无法检测到。同时,胸部X线片可提供有关循环血容量的有用信息。在急性呼吸窘迫综合征(ARDS)患者中,已显示出肺泡水肿具有特征性的外周和斑片状分布,且不存在支气管周围袖口征、间隔线和胸腔积液。在ARDS中,心脏右侧和主肺动脉扩大可能先于水肿的实际发生,并提供早期诊断的机会。ARDS病例的影像学“评分”与标准化至二氧化碳分压(PCO2)为40 mmHg时的氧分压(PO2,吸入氧分数(F1O2)= 0.21时测量)密切相关。三种主要形式的肺水肿(即心源性、肾性或补液过量性以及损伤性水肿)似乎具有可用于区分它们的影像学特征。通过将影像学征象作为判别分析的输入变量,已证实了这种方法的准确性和客观性。不同的血流动力学状况和血管外蛋白质渗透力变化可能是各种类型肺水肿影像学表现的主要潜在因素。