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附加瑜伽对减少强迫症(OCD)症状的有效性:一项随机对照试验。

Effectiveness of add-on yoga in reducing the symptoms of obsessive compulsive disorder (OCD): A randomized controlled trial.

机构信息

Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.

Department of Psychiatry Social work, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India.

出版信息

Asian J Psychiatr. 2024 Sep;99:104156. doi: 10.1016/j.ajp.2024.104156. Epub 2024 Jul 14.

Abstract

BACKGROUND

The standard treatments for Obsessive Compulsive Disorder (OCD) have been pharmacological and psychotherapeutic, with preliminary evidence for yoga as an intervention.

AIM

To test the short-term effects of a validated yoga intervention as an adjunct to medication in patients with OCD.

SETTINGS AND DESIGN

The study included patients diagnosed with OCD attending a tertiary psychiatry hospital in south India using a Randomized Controlled Trial (RCT) design.

METHODS

The study included 50 patients with OCD who were randomized into yoga group (n=25) and waitlist control group (n=25). All patients continued medication during the period of study. 42 subjects (Yoga=20, waitlist control=22) completed the study period of 4 weeks. Patients in the yoga group received 10 supervised sessions of a validated yoga module for OCD and continued home practice for next 20 days. Patients were rated on the Yale Brown Obsessive Compulsive Scale, Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale and Brown Assessment of Beliefs Scale at baseline and end of 4th week by raters who were blind to group status. For qualitative assessment, subjects were interviewed individually till data saturation was reached (n=11).

RESULTS

Patients randomized to yoga showed significant improvement in Obsessions (p-<0.001) (η2-1.3), Compulsions (p-0.007) (η2-0.8), Anxiety (p-0.002) (η2-1.0) and Depression (0.003) (η2-0.9) scores compared to patients in the waitlist control group. Qualitative results showed that yoga was efficacious in improving physical, mental, and overall health.

CONCLUSION

Yoga-based intervention as an adjunct to medication was effective in reducing symptoms in outpatients with OCD over 4 weeks.

摘要

背景

强迫症(OCD)的标准治疗方法是药物治疗和心理治疗,瑜伽作为一种干预手段已有初步证据。

目的

测试经过验证的瑜伽干预措施作为强迫症患者药物治疗辅助手段的短期效果。

设置和设计

这项研究包括在印度南部的一家三级精神病医院就诊的被诊断为 OCD 的患者,采用随机对照试验(RCT)设计。

方法

这项研究包括 50 名 OCD 患者,他们被随机分为瑜伽组(n=25)和候补对照组(n=25)。所有患者在研究期间都继续服用药物。42 名受试者(瑜伽组 20 名,候补对照组 22 名)完成了为期 4 周的研究。瑜伽组患者接受了 10 次经过验证的瑜伽 OCD 模块的监督课程,并在接下来的 20 天内继续在家练习。在基线和第 4 周结束时,由对组状态不知情的评估者对患者进行耶鲁-布朗强迫症量表、汉密尔顿焦虑量表、汉密尔顿抑郁量表和布朗信念量表评估。为了进行定性评估,对 11 名受试者进行了单独访谈,直到达到数据饱和(n=11)。

结果

与候补对照组的患者相比,随机分配到瑜伽组的患者在强迫观念(p-<0.001)(η2-1.3)、强迫行为(p-0.007)(η2-0.8)、焦虑(p-0.002)(η2-1.0)和抑郁(0.003)(η2-0.9)评分方面有显著改善。定性结果表明,瑜伽在改善身体、心理和整体健康方面是有效的。

结论

瑜伽为基础的干预措施作为药物治疗的辅助手段,在 4 周内对门诊强迫症患者的症状有明显的改善作用。

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