Boutelle Kerri N, Rhee Kyung E, Strong David R, Manzano Michael A, Bernard Rebecca S, Eichen Dawn M, Anderson Cheryl C A, Marcus Bess H, Akshoomoff Natacha, Crow Scott J
Department of Pediatrics, UC San Diego, La Jolla, California.
Herbert Wertheim School of Public Health and Human Longevity Science, UC San Diego, La Jolla, California.
Pediatrics. 2025 Feb 1;155(2). doi: 10.1542/peds.2024-066561.
Family-based behavioral treatment (FBT) for children with obesity is provided in weekly parent and child groups over 6 months. A guided self-help FBT program (gshFBT) is provided to the dyad in short meetings. Both interventions provide the same content; however, gshFBT provides this content in less time (FBT = 23 hours, gshFBT = 5.3 hours). This study aimed to evaluate whether gshFBT is noninferior to FBT on child weight loss and cost-effectiveness.
150 children aged between 7.0 and 12.9 years with a BMI between the 85th and 99.9th percentile and their parent were recruited and randomized to a 6-month program of gshFBT (n = 75) or FBT (n = 75) and were followed 12 months post-treatment.
A total of 150 children (mean age = 10.1 years, 49% female, mean BMIz = 2.09) and their parent (mean age = 41.5 years, 87% female, 45% Hispanic, 37% White non-Hispanic, 9.7% Asian, 4.8% Black, 7.3% other) were recruited from the San Diego Metropolitan area. Joint LME models showed that gshFBT was noninferior to FBT on child weight loss (ΔBMIz = -0.02 [90% credible interval [CI] -0.08-0.05, P = .65]; ΔBMIp95% = -1.57 [90% CI -4.46-1.31, P = .28]) and cost less (cost/dyad gshFBT = $1498; FBT = $2775).
The gshFBT program provided similar weight losses for children with less contact hours and with lower cost than FBT. The reduced time and ease of scheduling for the family in gshFBT will allow for an increased reach of treatment to a greater proportion of families in need.
针对肥胖儿童的家庭行为治疗（FBT）通过为期6个月的每周家长和儿童小组进行。引导式自助FBT项目（gshFBT）则在简短的会面中为亲子二元组提供。两种干预措施提供的内容相同；然而，gshFBT在更短的时间内提供这些内容（FBT = 23小时，gshFBT = 5.3小时）。本研究旨在评估gshFBT在儿童体重减轻和成本效益方面是否不劣于FBT。
招募了150名年龄在7.0至12.9岁之间、BMI处于第85至99.9百分位的儿童及其家长，并将他们随机分为gshFBT（n = 75）或FBT（n = 75）的6个月项目组，治疗后随访12个月。
共从圣地亚哥大都市区招募了150名儿童（平均年龄 = 10.1岁，49%为女性，平均BMIz = 2.09）及其家长（平均年龄 = 41.5岁，87%为女性，45%为西班牙裔，37%为非西班牙裔白人，9.7%为亚洲人，4.8%为黑人，7.3%为其他）。联合线性混合效应模型显示，gshFBT在儿童体重减轻方面不劣于FBT（ΔBMIz = -0.02 [90%可信区间[CI] -0.08 - 0.05，P = 0.65]；ΔBMIp95% = -1.
