College of Medicine, University of Arkansas for Medical Sciences Northwest, 2708 S. 48(th) St., Springdale, AR 72762, USA.
College of Medicine, University of Arkansas for Medical Sciences Northwest, 2708 S. 48(th) St., Springdale, AR 72762, USA.
Vaccine. 2024 Nov 14;42(25):126166. doi: 10.1016/j.vaccine.2024.126166. Epub 2024 Jul 30.
Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States. HPV-associated diseases are preventable with vaccination, but HPV vaccine coverage remains below other vaccines recommended during childhood and adolescence. We examined correlates of pediatric HPV vaccination among parents who have reported hesitancy toward the HPV vaccine. In addition to sociodemographic correlates, we investigated the relationships between the social process of healthcare provider recommendations and pediatric HPV vaccination.
We utilized phone survey data (N = 2201) collected in October 2022 via random digit dialing of Arkansan adults-Black and Hispanic respondents were oversampled for adequate representation. The survey was provided in English and Spanish. The analysis focused on a subsample of parents of children ages 9 to 17 years who reported HPV vaccine hesitancy (n = 201). Analyses include descriptive statistics, bivariate logistic regression, and multivariate logistic regression with Full Information Maximum Likelihood estimation.
A third (32.96%) of vaccine-hesitant parents reported their child(ren) had received at least one dose of the HPV vaccine. Only half (50.93%) of vaccine-hesitant parents received a healthcare provider recommendation to vaccinate their child(ren) between the ages of 9 and 17 against HPV. Adjusted odds of pediatric HPV vaccination were four times greater when vaccine-hesitant parents received a healthcare provider's recommendation (OR = 4.67; 95% CI[1.89, 11.55]) compared to when they had not. Pediatric HPV vaccination for parents whose provider did not recommend the HPV vaccine was not significantly different from those with no provider.
Healthcare provider recommendations are important for promoting HPV vaccination even among parents who are vaccine hesitant. Additional research is needed to understand why pediatric HPV vaccine recommendations are not made more often or consistently, particularly among vaccine-hesitant populations. This study demonstrates support for the growing body of research on hesitant adopters.
人乳头瘤病毒（HPV）是美国最常见的性传播感染。HPV 相关疾病可以通过疫苗接种预防，但 HPV 疫苗接种率仍低于儿童和青少年时期推荐的其他疫苗。我们研究了报告对 HPV 疫苗犹豫不决的父母中与儿科 HPV 疫苗接种相关的因素。除了社会人口统计学因素外，我们还研究了医疗服务提供者建议的社会过程与儿科 HPV 疫苗接种之间的关系。
我们利用 2022 年 10 月通过随机数字拨号对阿肯色州成年人进行的电话调查数据（N=2201）进行了分析-对黑人和西班牙裔受访者进行了超额抽样，以充分代表。调查提供了英语和西班牙语两种版本。分析集中在报告 HPV 疫苗犹豫不决的 9 至 17 岁儿童的父母的子样本上（n=201）。分析包括描述性统计、双变量逻辑回归以及使用完全信息最大似然估计的多变量逻辑回归。
三分之一（32.96%）的疫苗犹豫不决的父母报告说他们的孩子已经接种了至少一剂 HPV 疫苗。只有一半（50.93%）的疫苗犹豫不决的父母在 9 至 17 岁之间收到了医疗服务提供者接种 HPV 疫苗的建议。与未收到医疗服务提供者建议的父母相比，当疫苗犹豫不决的父母收到医疗服务提供者的建议时，他们的孩子接种 HPV 疫苗的可能性增加了四倍（OR=4.67；95%CI[1.89, 11.55]）。对于其提供者未建议接种 HPV 疫苗的父母，其儿科 HPV 疫苗接种率与未收到提供者建议的父母没有显著差异。
医疗服务提供者的建议对于促进 HPV 疫苗接种很重要，即使是在对疫苗犹豫不决的父母中也是如此。需要进一步研究为什么 HPV 疫苗建议没有更经常或更一致地提出，特别是在对疫苗犹豫不决的人群中。这项研究证明了对犹豫不决的接受者的研究不断增加的支持。
