Aquilina Jake M, Smith Myles W
UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390.
Synthesis (Stuttg). 2023 Nov;55(22):3725-3736. doi: 10.1055/a-2085-5934. Epub 2023 Jun 12.
The alkaloids are a relatively small family of plant-derived alkaloids that present an intriguing array of structural intricacy and biological properties. As such, these natural products have drawn interest from the synthetic community, resulting in creative total syntheses of several family members. This review showcases recent synthetic efforts towards these polycyclic alkaloids.
生物碱是一类相对较小的源自植物的生物碱家族,它们呈现出一系列引人入胜的结构复杂性和生物学特性。因此,这些天然产物引起了合成化学界的兴趣,导致了几个家族成员的创造性全合成。本综述展示了近期针对这些多环生物碱的合成研究成果。