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2007-2021 年巴西重要流行地区斑点热确诊和死亡相关因素。

Factors associated with the confirmation and death for Brazilian spotted fever in an important endemic area of the State of São Paulo, 2007-2021.

机构信息

Secretaria de Saúde de Americana, Unidade de Vigilância em Saúde, Americana, SP, Brasil.

Universidade Estadual de Campinas, Programa de Pós-Graduação em Saúde Coletiva, Campinas, SP, Brasil.

出版信息

Rev Soc Bras Med Trop. 2024 Jul 29;57:e00708. doi: 10.1590/0037-8682-0617-2023. eCollection 2024.

DOI:10.1590/0037-8682-0617-2023
PMID:39082523
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11290846/
Abstract

BACKGROUND

We evaluated the predictive factors for case confirmation and death from Brazilian spotted fever in an endemic area of Southeastern Brazil.

METHODS

A cross-sectional study was conducted. All suspected cases reported between 2007 and 2021 were analyzed using two logistic regression models.

RESULTS

60 cases were confirmed. Male sex, age group of 40-59 years, tick parasitism, presence of capybaras or horses, exanthema and hospitalization were positively associated with confirmation. Death was associated with a longer period between first symptom-hospitalization and shorter treatment.

CONCLUSIONS

Complete clinical evaluation and information on risk exposure are key to early suspicion, diagnosis, treatment and prevention of deaths.

摘要

背景

我们评估了巴西东南部流行地区巴西斑疹热病例确诊和死亡的预测因素。

方法

进行了一项横断面研究。使用两个逻辑回归模型分析了 2007 年至 2021 年期间报告的所有疑似病例。

结果

确诊 60 例。男性、40-59 岁年龄组、蜱虫寄生、有水豚或马、出疹和住院与确诊呈正相关。死亡与首次症状-住院时间延长和治疗时间缩短有关。

结论

完整的临床评估和风险暴露信息是早期怀疑、诊断、治疗和预防死亡的关键。

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本文引用的文献

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Ticks Tick Borne Dis. 2020 Sep;11(5):101463. doi: 10.1016/j.ttbdis.2020.101463. Epub 2020 May 7.
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Predictive Factors for Fatal Tick-Borne Spotted Fever in Brazil.巴西蜱传斑点热致死的预测因素。
Zoonoses Public Health. 2017 Nov;64(7):e44-e50. doi: 10.1111/zph.12345. Epub 2017 Feb 7.
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A fatal case of Brazilian spotted fever in a non-endemic area in Brazil: the importance of having health professionals who understand the disease and its areas of transmission.
巴西非流行地区的一例巴西斑疹热致死病例:具备了解该疾病及其传播区域的卫生专业人员的重要性。
Rev Soc Bras Med Trop. 2016 Sep-Oct;49(5):653-655. doi: 10.1590/0037-8682-0088-2016.
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High Seroprevalence for Rickettsia rickettsii in Equines Suggests Risk of Human Infection in Silent Areas for the Brazilian Spotted Fever.马身上立氏立克次体的高血清阳性率表明巴西斑疹热无声区域存在人类感染风险。
PLoS One. 2016 Apr 11;11(4):e0153303. doi: 10.1371/journal.pone.0153303. eCollection 2016.
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Risk factors associated with the transmission of Brazilian spotted fever in the Piracicaba river basin, State of São Paulo, Brazil.巴西圣保罗州皮拉西卡巴河流域与巴西斑疹热传播相关的风险因素。
Rev Soc Bras Med Trop. 2015 Jan-Feb;48(1):11-7. doi: 10.1590/0037-8682-0281-2014. Epub 2015 Jan 1.
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Clin Infect Dis. 2015 Jun 1;60(11):1659-66. doi: 10.1093/cid/civ116. Epub 2015 Feb 19.
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