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嗜铬细胞瘤的手术治疗:六只犬的技术、并发症及结果

Surgical treatment of pheochromocytoma: technique, complications, and results in six dogs.

作者信息

Gilson S D, Withrow S J, Orton E C

机构信息

Comparative Oncology Unit, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins.

出版信息

Vet Surg. 1994 May-Jun;23(3):195-200. doi: 10.1111/j.1532-950x.1994.tb00472.x.

Abstract

Six dogs were diagnosed with pheochromocytoma and staged according to the World Health Organization's system for tumor classification. Two dogs had benign tumors (T1, N0, M0) and four dogs had malignant tumors (T2, N0, M1 or T3, N0, M0). All dogs had adrenalectomy, two dogs had concurrent nephrectomy, and three dogs had concurrent resection of a tumor thrombus from the vena cava. Anesthetic complications occurred in five dogs, including wide variations in heart rate (four dogs), blood pressure (five dogs), and cardiac arrhythmias (one dog). One dog died 12 hours after surgery from partial dehiscence of the suture line and hemorrhage from the vena cava, and one dog died 6 days after surgery during general anesthesia for treatment of laryngeal paralysis. Four dogs survived from 3 to 23 months (median, 15 months). One dog remained hypertensive after surgery. Benign and malignant pheochromocytomas seem to be amenable to surgical resection.

摘要

六只犬被诊断为嗜铬细胞瘤,并根据世界卫生组织肿瘤分类系统进行分期。两只犬患有良性肿瘤(T1,N0,M0),四只犬患有恶性肿瘤(T2,N0,M1或T3,N0,M0)。所有犬均接受了肾上腺切除术,两只犬同时进行了肾切除术,三只犬同时从腔静脉切除了肿瘤血栓。五只犬出现麻醉并发症,包括心率大幅波动(四只犬)、血压波动(五只犬)和心律失常(一只犬)。一只犬在术后12小时因缝线部分裂开和腔静脉出血死亡,一只犬在术后6天因喉麻痹接受全身麻醉治疗时死亡。四只犬存活了3至23个月(中位数为15个月)。一只犬术后仍有高血压。良性和恶性嗜铬细胞瘤似乎都适合手术切除。

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