靶向短信提醒在结直肠癌筛查中的有效性和可接受性：随机对照试验（M-TICS 研究）。

Effectiveness and Acceptability of Targeted Text Message Reminders in Colorectal Cancer Screening: Randomized Controlled Trial (M-TICS Study).

机构信息

Cancer Screening Unit, Institut Català d'Oncologia (ICO), L'Hospitalet de Llobregat, Spain.

Early Detection of Cancer Group, Epidemiology, Public Health, Cancer Prevention and Palliative Care Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Spain.

出版信息

JMIR Public Health Surveill. 2024 Jul 31;10:e57959. doi: 10.2196/57959.

DOI:10.2196/57959

PMID:39083331

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11325104/

Abstract

BACKGROUND

Mobile phone-based SMS text message reminders have the potential to improve colorectal cancer screening participation rates.

OBJECTIVE

This study assessed the effectiveness and acceptability of adding targeted SMS text message reminders to the standard procedure for those who picked up but did not return their screening kit at the pharmacy within 14 days in a colorectal cancer screening program in Catalonia, Spain.

METHODS

We performed a randomized control trial among individuals who picked up a fecal immunochemical test (FIT) kit for colorectal cancer screening at the pharmacy but did not return it within 14 days. The intervention group (n=4563) received an SMS text message reminder on the 14th day of kit pick up and the control group (n=4806) received no reminder. A 30-day reminder letter was sent to both groups if necessary. The main primary outcome was the FIT completion rate within 30, 60, and 126 days from FIT kit pick up (intention-to-treat analysis). A telephone survey assessed the acceptability and appropriateness of the intervention. The cost-effectiveness of adding an SMS text message reminder to FIT completion was also performed.

RESULTS

The intervention group had higher FIT completion rates than the control group at 30 (64.2% vs 53.7%; P<.001), 60 (78.6% vs 72.0%; P<.001), and 126 (82.6% vs 77.7%; P<.001) days. Participation rates were higher in the intervention arm independent of sex, age, socioeconomic level, and previous screening behavior. A total of 339 (89.2%) interviewees considered it important and useful to receive SMS text message reminders for FIT completion and 355 (93.4%) preferred SMS text messages to postal letters. We observed a reduction of US $2.4 per participant gained in the intervention arm for invitation costs compared to the control arm.

CONCLUSIONS

Adding an SMS text message reminder to the standard procedure significantly increased FIT kit return rates and was a cost-effective strategy. SMS text messages also proved to be an acceptable and appropriate communication channel for cancer screening programs.

TRIAL REGISTRATION

ClinicalTrials.gov NCT04343950; https://www.clinicaltrials.gov/study/NCT04343950.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1371/journal.pone.0245806.

摘要

背景

基于手机的短信提醒有可能提高结直肠癌筛查的参与率。

目的

本研究评估了在西班牙加泰罗尼亚地区的结直肠癌筛查计划中，对于在 14 天内从药房取走但未归还筛查工具包的人群，在标准程序中添加有针对性的短信提醒对提高筛查参与率的有效性和可接受性。

方法

我们对在药房取走粪便免疫化学测试（FIT）试剂盒但在 14 天内未归还的人群进行了一项随机对照试验。干预组（n=4563）在取试剂盒的第 14 天收到短信提醒，对照组（n=4806）未收到提醒。如果需要，两组都将收到 30 天的提醒信。主要的初级结局是从 FIT 试剂盒取走后 30、60 和 126 天内完成 FIT 的比例（意向治疗分析）。一项电话调查评估了干预措施的可接受性和适当性。还对添加短信提醒对 FIT 完成的成本效益进行了评估。

结果

干预组在 30 天（64.2% vs 53.7%；P<.001）、60 天（78.6% vs 72.0%；P<.001）和 126 天（82.6% vs 77.7%；P<.001）时完成 FIT 的比例高于对照组。干预组的参与率高于对照组，与性别、年龄、社会经济水平和先前的筛查行为无关。共有 339 名（89.2%）受访者认为收到 FIT 完成的短信提醒很重要和有用，355 名（93.4%）受访者更喜欢短信而不是邮件。与对照组相比，干预组邀请参与者的成本每增加 1 人可节省 2.4 美元。