Dr. Elie E. Rebeiz Department of Otolaryngology-Head and Neck Surgery, Tufts Medical Center, 860 Washington St Building 1st Floor, Boston, MA, 02111, USA.
Boston University School of Medicine, 72 East Concord St, Boston, MA, 02118, USA; Boston University School of Public Health, 715 Albany St, Boston, MA, 02118, USA; Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, 12631 East 17th Avenue 3001, Aurora, CO, 80045, USA.
Int J Pediatr Otorhinolaryngol. 2024 Aug;183:112051. doi: 10.1016/j.ijporl.2024.112051. Epub 2024 Jul 24.
This study aims to determine the overall incidence of medical and surgical admissions related to non-tuberculous mycobacterial cervicofacial lymphadenitis (NTMCL) and determine if rates vary by geographic region in the US. It also aims to assess if the relative frequency of varying treatment modalities for NTMCL differ among geographic regions.
Population-based inpatient registry analysis.
Academic medical center.
The Kids' Inpatient Database (2016 and 2019) was used to determine NTMCL-related admissions and common head and neck procedures performed during these admissions were identified. Analysis was performed on regional differences in demographic factors and procedures performed during NTMCL-related admissions.
There were 159 weighted admissions (1.31 per 100,000) for NTMCL in 2016 and 2019 in the US, with the Midwest having the highest proportion of NTML-related admissions (1.59:100,000). NTMCL-related admissions were 2.21 times as likely to be elective rather than non-elective in the Midwest when compared to all other geographic regions (p = 0.038). The Midwest was 2.83 times as likely to treat with surgery (p = 0.011), while the Northeast was negatively associated with performing procedures (OR 0.38; p = 0.026). In the Midwest, significantly more excisional surgeries were preformed when compared to other regions, with an OR of 2.98 (p = 0.003).
The Midwest had the highest incidence of pediatric NTMCL-related admissions and was more likely to perform excisional surgery as primary NTMCL treatment. Regions that rarely see pediatric NTMCL have a more inconsistent approach to management.
本研究旨在确定与非结核分枝杆菌颈淋巴结炎（NTMCL）相关的医疗和手术入院的总体发生率，并确定美国不同地区的发病率是否存在差异。本研究还旨在评估不同地理区域的 NTMCL 治疗方式的相对频率是否存在差异。
基于人群的住院患者登记分析。
学术医疗中心。
使用儿童住院数据库（2016 年和 2019 年）确定与 NTMCL 相关的入院病例，并确定在此类入院病例中进行的常见头颈部手术。分析 NTMCL 相关入院病例的地区差异与操作。
2016 年和 2019 年，美国共有 159 例 NTMCL 相关入院病例（每 10 万人中有 1.31 例），中西部地区 NTMCL 相关入院病例比例最高（每 10 万人中有 1.59 例）。与所有其他地理区域相比，中西部地区 NTMCL 相关入院病例中，择期入院的可能性是急诊入院的 2.21 倍（p=0.038）。与其他地区相比，中西部地区更倾向于手术治疗（p=0.011），而东北地区进行手术的可能性较低（OR 0.38；p=0.026）。在中西部地区，与其他地区相比，更多地进行了切除术，OR 为 2.98（p=0.003）。
中西部地区儿童 NTMCL 相关入院率最高，更倾向于将切除术作为 NTMCL 的主要治疗方法。很少见到儿科 NTMCL 的地区在管理上的方法更加不一致。
