Pau H W, Straehler-Pohl H J, Exner M
HNO. 1985 Nov;33(11):485-8.
The microflora of the oral cavity and pharynx were examined in 28 patients undergoing radiotherapy for cancer of the upper aerodigestive tract. We found no correlation between yeast flora and mucositis: early mucositis occurred between 10 and 20 gy. independent of the concentration of yeast. During radiotherapy the number of patients with detectable yeasts rose from 12 to 22 of the 28. There was a tenfold increase of mean values for yeasts during irradiation, whereas the normal flora (eg. streptococci) remained unchanged. The value of an antifungal local therapy for the prevention of yeast-induced complications is discussed.
对28例接受上呼吸道消化道癌症放射治疗的患者的口腔和咽部微生物群进行了检查。我们发现酵母菌菌群与粘膜炎之间没有相关性：早期粘膜炎发生在10至20戈瑞之间，与酵母菌浓度无关。在放射治疗期间，28例患者中可检测到酵母菌的人数从12例增加到22例。照射期间酵母菌的平均值增加了10倍，而正常菌群（如链球菌）保持不变。讨论了抗真菌局部治疗在预防酵母菌引起的并发症方面的价值。
