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在咽喉癌和口腔癌放射治疗中采用每日三次分割的照射方案。

Irradiation scheme using three daily fractions in the radiation therapy of pharyngeal and oral carcinomas.

作者信息

Durkovský J, Jancina J, Siracká E, Krajci M

出版信息

Neoplasma. 1984;31(2):213-22.

PMID:6717690
Abstract

A group of 34 patients were treated by irradiation using 3 daily fractions of 1 Gy each at 4 h intervals. The overall TD in all of the patients was 60 Gy administered within 26 days. The irradiation was carried out by telecurietherapy utilizing 60Co. Twenty-eight patients had the tumor in the oropharynx, 1 in the hypopharynx, 1 in the oro- and hypopharynx and 4 in the oral cavity. There was a prevalence of advanced clinical stages. At present 25 of the patients are living, 21 of them without clinical symptoms of the disease. The skin reacted to irradiation only with a slight erythema and hyperpigmentation. Irradiation reactions in the oropharyngeal and oral mucosa were grave and were accompanied by significant subjective complaints. No post-irradiation complications were observed.

摘要

一组34例患者接受放疗,每天分3次照射,每次1 Gy,间隔4小时。所有患者的总剂量为60 Gy,在26天内给予。放疗采用60Co远距离后装治疗。28例患者肿瘤位于口咽,1例位于下咽,1例同时累及口咽和下咽,4例位于口腔。临床分期多为晚期。目前25例患者存活,其中21例无疾病临床症状。皮肤对放疗仅出现轻微红斑和色素沉着。口咽和口腔黏膜的放疗反应严重,并伴有明显的主观不适。未观察到放疗后并发症。

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1
Irradiation scheme using three daily fractions in the radiation therapy of pharyngeal and oral carcinomas.在咽喉癌和口腔癌放射治疗中采用每日三次分割的照射方案。
Neoplasma. 1984;31(2):213-22.
2
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Radiation therapy of carcinoma of the oropharynx.口咽癌的放射治疗
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Br J Cancer Suppl. 1980 Apr;4:14-6.