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哺乳动物皮肤和口腔上皮颗粒层的薄片制备物。

Sheet preparations of the stratum granulosum from mammalian skin and oral epithelium.

作者信息

Hume W J, Moore J K

出版信息

J Anat. 1985 Jun;140 ( Pt 4)(Pt 4):669-78.

PMID:3908423
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1165091/
Abstract

Acetic acid has been used to obtain sheet preparations of the stratum granulosum from epidermis and oral epithelium of mouse, rat, hamster and man. Clear differences exist in the appearance of nuclei and keratohyalin granules and in the extent of cell overlapping. In the ventral surface of mouse tongue, the number of granular cells in a sheet preparation is relatively constant (average +/- S.D. = 1633 +/- 160/mm2). Cell suspensions show a greater variation in the area and maximum diameter of the cells in ventral tongue compared to mouse ear epidermis. As might be expected, this is reflected in the pattern of stacking of suprabasal cells into discrete columns in ear, but not in ventral tongue epithelium. The ratio of granular to basal cells for different sites and species is fairly constant, with an average of approximately 10:1. The pattern of nuclear breakdown can be followed, beginning in the middle of the nucleus and gradually extending outwards, often in an irregular manner until the entire nucleus is removed.

摘要

乙酸已被用于从小鼠、大鼠、仓鼠和人类的表皮及口腔上皮获取颗粒层的片状制剂。细胞核和透明角质颗粒的外观以及细胞重叠程度存在明显差异。在小鼠舌腹面，片状制剂中颗粒细胞的数量相对恒定（平均值±标准差=1633±160/mm²）。与小鼠耳部表皮相比，细胞悬液显示舌腹面细胞的面积和最大直径变化更大。正如预期的那样，这反映在耳中基底上层细胞堆积成离散柱状的模式中，而在舌腹面上皮中则没有。不同部位和物种的颗粒细胞与基底细胞的比例相当恒定，平均约为10:1。核解体的模式可以被追踪到，从细胞核中部开始，通常以不规则的方式逐渐向外扩展，直到整个细胞核消失。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9f/1165091/d32bc8a23d35/janat00196-0122-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9f/1165091/6310c1a9a4cb/janat00196-0122-c.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9f/1165091/c74f029ebaf6/janat00196-0122-e.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9f/1165091/e2031dbef649/janat00196-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9f/1165091/242d5f4d7413/janat00196-0127-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9f/1165091/f4b40076f8af/janat00196-0127-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d9f/1165091/52f9f492e2c0/janat00196-0127-d.jpg
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本文引用的文献

1
Proliferative units in stratified squamous epithelium.
Clin Exp Dermatol. 1983 Jan;8(1):95-106. doi: 10.1111/j.1365-2230.1983.tb01749.x.
2
Ordered structure of the stratum corneum of mammalian skin.
Nature. 1969 May 31;222(5196):881-2. doi: 10.1038/222881a0.
3
The ultrastructure of binucleate keratinocytes and binucleation in palatal mucosa of guinea pigs.豚鼠腭黏膜中双核角质形成细胞的超微结构及双核化
Cell Tissue Res. 1974 Jul 3;150(1):113-23. doi: 10.1007/BF00220385.
4
Observations on the ultrastructure of the buccal epithelium of the rat.大鼠颊上皮超微结构的观察
Arch Oral Biol. 1971 Sep;16(9):1071-88. doi: 10.1016/0003-9969(71)90212-3.
5
The epidermal proliferative unit: the possible role of the central basal cell.表皮增殖单位：中央基底细胞的可能作用。
Cell Tissue Kinet. 1974 Jan;7(1):77-88. doi: 10.1111/j.1365-2184.1974.tb00401.x.
6
Circadian rhythms of presumptive stem cells in three different epithelia of the mouse.小鼠三种不同上皮中假定干细胞的昼夜节律。
Cell Tissue Kinet. 1977 Nov;10(6):557-68. doi: 10.1111/j.1365-2184.1977.tb00312.x.