Kostares Evangelos, Kostare Georgia, Kostares Michael, Tsakris Athanasios, Kantzanou Maria
Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Department of Microbiology, Medical School, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
J Stomatol Oral Maxillofac Surg. 2025 Feb;126(1):101995. doi: 10.1016/j.jormas.2024.101995. Epub 2024 Jul 29.
Our research aims to assess the prevalence of surgical site infections (SSI) following impacted mandibular third molar extractions. Two independent reviewers conducted a comprehensive systematic literature search across Medline, Scopus and Cochrane Central databases. The pooled prevalence, accompanied by 95% confidence intervals (CI), was calculated. Quality assessments, outlier and influential analyses were performed. Our meta-analysis included seventeen eligible studies, encompassing a total of 37,585 impacted mandibular third molar extractions. The overall prevalence of SSI following impacted mandibular third molar extractions was estimated at 1.7% (95% CI 1%-2.6%), indicating considerable heterogeneity among the studies. No study was identified as critically influential. This study highlights the imperative for future well-constructed prospective and retrospective investigations to deepen our understanding of the etiological nuances and refine management approaches for this prevalent postoperative complication.
我们的研究旨在评估下颌阻生第三磨牙拔除术后手术部位感染（SSI）的发生率。两名独立评审员对Medline、Scopus和Cochrane Central数据库进行了全面的系统文献检索。计算了合并发生率及95%置信区间（CI）。进行了质量评估、异常值和影响分析。我们的荟萃分析纳入了17项符合条件的研究，共涉及37585例下颌阻生第三磨牙拔除术。下颌阻生第三磨牙拔除术后SSI的总体发生率估计为1.7%（95%CI 1%-2.6%），表明各研究之间存在相当大的异质性。未发现有研究具有关键影响力。本研究强调，未来必须开展精心设计的前瞻性和回顾性调查，以加深我们对这种常见术后并发症病因细微差别的理解，并完善管理方法。
