Kubo Moeko, Horie Ichiro, Tokumitsu Jun-Ichi, Tsuchiyama Hideyuki, Nakaji Erika, Naganobu Keiko, Arimori Haruka, Haraguchi Ai, Ikeoka Toshiyuki, Kawakami Atsushi
Department of Diabetes and Endocrinology, Isahaya General Hospital, Japan Community Health Care Organization, Japan.
Department of Endocrinology and Metabolism, Nagasaki University Hospital, Japan.
Intern Med. 2025 Mar 1;64(5):735-740. doi: 10.2169/internalmedicine.4112-24. Epub 2024 Aug 1.
Exercise-associated hyponatremia (EAH) is a life-threatening dilutional hyponatremia that typically occurs during or immediately after exercise in endurance athletes. A 49-year-old actress experienced dizziness 15 min after a 2-h stage performance while drinking several bottles of water. Thirty minutes later, the patient fell unconscious and was hospitalized. On admission, she showed dilutional hyponatremia (117 mmol/L) with extremely elevated arginine vasopressin (11.3 pg/mL). After initial treatment with 3% saline, her sodium levels immediately increased, and she recovered consciousness without developing subsequent osmotic demyelination syndrome. This case emphasizes the need for caution against excessive fluid intake during and/or after exercise to avoid EAH, even in non-athletes.
运动相关性低钠血症(EAH)是一种危及生命的稀释性低钠血症,通常发生在耐力运动员运动期间或运动刚结束后。一名49岁的女演员在进行了2小时的舞台表演并喝了几瓶水后15分钟出现头晕。30分钟后,患者失去意识并住院。入院时,她表现为稀释性低钠血症(117 mmol/L),精氨酸加压素极度升高(11.3 pg/mL)。经3%盐水初步治疗后,她的钠水平立即升高,且恢复了意识,未发生随后的渗透性脱髓鞘综合征。该病例强调,即使对于非运动员,在运动期间和/或运动后也需谨慎避免过量饮水以预防运动相关性低钠血症。