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评估急性创伤性脊髓损伤后钙调节失调的初步筛查方法:回顾性研究。

Evaluating initial screening practices for calcium dysregulation after acute traumatic spinal cord injury: a retrospective review.

机构信息

Department of Physical Medicine and Rehabilitation, VCU Health, Richmond, VA, USA.

Department of Internal Medicine, Division of Endocrinology, VCU Health, Central Virginia Veteran's Affairs Healthcare System, Richmond, VA, USA.

出版信息

Spinal Cord Ser Cases. 2024 Jul 31;10(1):54. doi: 10.1038/s41394-024-00663-0.

Abstract

OBJECTIVES

The purpose of this study was to determine the frequency of which calcium homeostasis markers are obtained in the acute setting after an initial traumatic spinal cord injury (TSCI).

DESIGN

Retrospective chart review of a limited data set linking ICD 10 codes designating TSCI to corresponding calcium homeostasis markers for patients with an initial chart encounter for TSCI.

SETTING

A level 1 trauma center in Virginia, United States METHODS: The statistical software SPSS was used to calculate summary statistics including frequency, mean, and standard deviation for calcium homeostasis markers (basic metabolic panel, magnesium, spot urine calcium, testosterone panel, liver function tests, Vitamin D level, C-telopeptide, parathyroid hormone, celiac panel, DXA imaging report) as well as the mean and standard deviation for time to first check of the marker.

RESULTS

Most markers were not obtained besides calcium. Only 10 of 80 (12.5%) of subjects had a Vitamin D level (mean 28, SD 23) checked during acute admission (mean days to check 1.5, SD 1.6), with most other markers checked much less frequently.

CONCLUSIONS

Most calcium homeostasis markers were not checked on acute admission after TSCI. Future studies on implementing a standardized calcium homeostasis marker protocol for monitoring and potential medical intervention should be explored.

摘要

目的

本研究旨在确定在初次创伤性脊髓损伤(TSCI)后的急性治疗环境中,钙稳态标志物的获取频率。

设计

回顾性图表审查,将 ICD-10 代码指定为 TSCI 的有限数据集与 TSCI 初始图表就诊患者的钙稳态标志物相关联。

地点

美国弗吉尼亚州的 1 级创伤中心

方法

使用统计软件 SPSS 计算钙稳态标志物(基本代谢面板、镁、尿液钙点、睾酮面板、肝功能检查、维生素 D 水平、C 端肽、甲状旁腺激素、乳糜泻面板、DXA 成像报告)的频率、均值和标准差,以及标志物首次检查的均值和标准差。

结果

除钙外,大多数标志物都未被检测到。在急性入院期间,仅 80 名患者中的 10 名(12.5%)进行了维生素 D 水平(平均 28,标准差 23)检查(平均检查天数 1.5,标准差 1.6),其他大多数标志物检查频率要低得多。

结论

TSCI 后,在急性入院期间,大多数钙稳态标志物都未被检测到。应探索实施标准化钙稳态标志物监测和潜在医学干预方案的未来研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a822/11291971/2e0191a3fc2b/41394_2024_663_Fig1_HTML.jpg

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