Yahia Manel, Laabidi B, M'sakni Issam, Bougrine Fethi, Bouziani Ammar
Tunis Med. 2016 Oct;94(10):622-625.
Intraosseous hibernoma is a rare benign bone tumor, with only 4 cases reported in English literature.
In this report, we describe a 42-year-old man with no past medical history and right chest pain. Imaging studies showed an osteolytic lesion with fat attenuation lesion in the right fourth rib. The lesion was completely resected and microscopic study showed mildly thickened bone trabeculae and multivacuolated brown fat cells replacing the normal white fat and hematopoietic elements. The diagnostic of intraosseous hibernoma was made.
Although it is rare, hibernoma should be included in the differential diagnosis of lipomatous tumors.
骨内冬眠瘤是一种罕见的良性骨肿瘤,英文文献中仅报道过4例。
在本报告中,我们描述了一名42岁、无既往病史且有右胸痛的男性。影像学检查显示右第四肋骨有一个溶骨性病变,伴有脂肪衰减病变。该病变被完整切除,显微镜检查显示骨小梁轻度增厚,多泡状棕色脂肪细胞取代了正常的白色脂肪和造血成分。诊断为骨内冬眠瘤。
尽管罕见,但冬眠瘤应列入脂肪性肿瘤的鉴别诊断中。