Suppr超能文献

探讨美国成年人 2 型糖尿病与粪便失禁之间的关联:一项大型横断面研究的启示。

Exploring the association between type 2 diabetes and fecal incontinence in american adults: insights from a large cross-sectional study.

机构信息

Department of Emergency Medicine, the Fourth Medical Center of PLA General Hospital, 51 Fucheng Road, Haidian District, Beijing, 100048, P.R. China.

Plastic and Reconstructive Surgery Unit, Department of Burns and Plastic Surgery, the Fourth Medical Center of PLA General Hospital, Beijing, 100048, P.R. China.

出版信息

Int J Colorectal Dis. 2024 Jul 31;39(1):121. doi: 10.1007/s00384-024-04697-6.

Abstract

BACKGROUND

The relationship between fecal incontinence (FI) and type 2 diabetes (T2D) has been well recognized, but a comprehensive understanding of this relationship is lacking, taking into account demographic factors and lifestyle variables.

METHODS

Using a cross-sectional approach, 13,510 adults aged 20 years and older were identified from the 2005-2010 National Health and Nutrition Examination Survey. Multivariate logistic regression models were used to calculate the adjusted odds ratios (ORs), and further subgroup analyses and propensity score analysis were performed to ensure stable results.

RESULTS

Among 13,510 adults, 11.2% had T2D, and 8.8% had FI. We found a strong T2D-FI link (OR: 1.30; 95% CI: 1.09-1.54, P < 0.001), even after adjusting for covariates. Age > 45 was a critical factor, with a stronger T2D-FI association. Sedentary behavior (OR: 1.41; 95% CI: 1.15-1.73) in T2D patients were associated with FI.

CONCLUSIONS

Our study highlights the significant T2D-FI link in US adults, especially in older T2D patients. Lifestyle changes may reduce FI risk. More research is needed for causality and mechanisms.

摘要

背景

粪便失禁(FI)与 2 型糖尿病(T2D)之间的关系已得到充分认识,但考虑到人口统计学因素和生活方式变量,对这种关系的全面了解仍有所欠缺。

方法

使用横断面研究方法,从 2005-2010 年全国健康和营养调查中确定了 13510 名年龄在 20 岁及以上的成年人。使用多变量逻辑回归模型计算调整后的优势比(OR),并进行进一步的亚组分析和倾向评分分析,以确保结果稳定。

结果

在 13510 名成年人中,11.2%患有 T2D,8.8%患有 FI。我们发现 T2D-FI 之间存在很强的关联(OR:1.30;95%CI:1.09-1.54,P<0.001),即使在调整了混杂因素后也是如此。年龄>45 岁是一个关键因素,与更强的 T2D-FI 关联有关。T2D 患者的久坐行为(OR:1.41;95%CI:1.15-1.73)与 FI 有关。

结论

我们的研究强调了美国成年人中 T2D-FI 之间的显著关联,特别是在年龄较大的 T2D 患者中。生活方式的改变可能会降低 FI 的风险。需要进一步研究因果关系和机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2ce/11291540/4e60d583a688/384_2024_4697_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验