Department of Anorectal surgery, Xiyuan Hospital, China Academy of Chinese Medical Sciences, 1 Xiyuan Playground, Haidian District, Beijing, China.
Department of Oncology, Guang' anmen Hospital, China Academy of Chinese Medical Sciences, 5 Beixiange, Xicheng District, Beijing, China.
J Psychosom Res. 2023 Jul;170:111377. doi: 10.1016/j.jpsychores.2023.111377. Epub 2023 May 15.
Currently, research on the relationship between fecal incontinence (FI) and suicidal ideation is very limited. This study aims to evaluate whether FI is associated with suicidal ideation among US adults.
In this cross-sectional study, 13,480 adults aged 20 years and older were selected from the National Health and Nutrition Examination Survey 2005-2010. Monthly loss of solid, liquid, or mucous stool was defined as FI. As part of the Patient Health Questionnaire-9, item 9 assessed suicidal ideation. Models of multivariate logistic regression were used to calculate adjusted odds ratios. A subgroup analysis was carried out to ensure that the results were stable.
It was found that FI was associated with an increased risk of suicidal ideation after controlling for baseline characteristics, risk behaviors, and comorbid conditions such as depression (OR: 1.60, 95%CI: 1.24-2.08, P < 0.001). In subgroup analyses, FI remained significantly associated with suicidal ideation among participants aged 45 years and older, with odds ratios and 95% confidence intervals of 1.62 (1.11-2.38) and 2.49 (1.51-4.13), respectively. For age category <45 years, the association between FI and suicidal ideation weakened (OR: 1.02, 95%CI: 0.60-1.75, P = 0.932).
In conclusion, this study showed that FI was significantly associated with suicidal ideation. Patients aged middle-aged and older are at high risk and should be the focus of screening and timely intervention for suicidal ideation.
目前，关于粪便失禁（FI）与自杀意念之间关系的研究非常有限。本研究旨在评估 FI 是否与美国成年人的自杀意念相关。
在这项横断面研究中，从 2005-2010 年全国健康和营养调查中选择了 13480 名年龄在 20 岁及以上的成年人。每月固体、液体或黏液粪便丢失定义为 FI。作为患者健康问卷-9 的一部分，第 9 项评估自杀意念。使用多变量逻辑回归模型计算调整后的优势比。进行亚组分析以确保结果稳定。
在控制基线特征、风险行为和共病情况（如抑郁症）后，发现 FI 与自杀意念的风险增加相关（OR：1.60，95%CI：1.24-2.08，P<0.001）。在亚组分析中，FI 仍然与 45 岁及以上参与者的自杀意念显著相关，其优势比和 95%置信区间分别为 1.62（1.11-2.38）和 2.49（1.51-4.13）。对于年龄<45 岁的人群，FI 与自杀意念之间的关联减弱（OR：1.02，95%CI：0.60-1.75，P=0.932）。
总之，本研究表明 FI 与自杀意念显著相关。中年及以上患者风险较高，应作为自杀意念筛查和及时干预的重点。
