Kommoju Anilkumar, Snehita Kattamuri, Sowjanya Kandi, Mukkamala Saratchandra Babu, Padala Kishor
Department of Chemistry, Central Tribal University of Andhra Pradesh, Vizianagaram, Andhra Pradesh-535003, India.
Chem Commun (Camb). 2024 Aug 20;60(68):8946-8977. doi: 10.1039/d4cc02914c.
Alkene carbofunctionalization reactions have great potential for synthesizing complex molecules and constructing complex structures in natural products and medicinal chemistry. Recently, dual photoredox/nickel catalysis has emerged as a novel strategy for alkene carbofunctionalization. Nickel offers numerous advantages over other transition metals, such as cost-effectiveness, abundance, and low toxicity, and moreover, it has many oxidation states. Nickel catalysts exhibit excellent catalytic activity in dual photoredox/transition metal catalysis, facilitating the formation of carbon-carbon or carbon-heteroatom bonds in organic transformations. This review highlights the latest advancements in dual photoredox/nickel-catalyzed alkene carbofunctionalizations and includes the literature published from 2020 to 2024.
烯烃碳官能团化反应在合成复杂分子以及构建天然产物和药物化学中的复杂结构方面具有巨大潜力。最近，双光氧化还原/镍催化已成为烯烃碳官能团化的一种新策略。与其他过渡金属相比，镍具有许多优势，如成本效益高、储量丰富和低毒性，而且它有多种氧化态。镍催化剂在双光氧化还原/过渡金属催化中表现出优异的催化活性，有助于在有机转化中形成碳-碳或碳-杂原子键。本综述重点介绍了双光氧化还原/镍催化的烯烃碳官能团化的最新进展，并涵盖了2020年至2024年发表的文献。
