Zhu Chen, Yue Huifeng, Chu Lingling, Rueping Magnus
KAUST Catalysis Center , KCC , King Abdullah University of Science and Technology , KAUST , Thuwal 23955-6900 , Saudi Arabia . Email:
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials , Center for Advanced Low-Dimension Materials , College of Chemistry , Chemical Engineering and Biotechnology , Donghua University , Shanghai 201620 , China . Email:
Chem Sci. 2020 Apr 1;11(16):4051-4064. doi: 10.1039/d0sc00712a. eCollection 2020 Apr 28.
Cascade reactions that produce multiple chemical bonds in one synthetic operation are important in the efficient construction of complex molecules. In addition, photoredox and nickel dual catalysis opens a new and powerful avenue for transition-metal-catalyzed cross-coupling reactions. By combining these two concepts, photoredox and nickel dual-catalyzed cascade reactions have been recently established, and they provide an efficient and mild method for accessing a series of valuable organic compounds.
在一个合成操作中产生多个化学键的级联反应对于复杂分子的高效构建很重要。此外，光氧化还原和镍双催化为过渡金属催化的交叉偶联反应开辟了一条新的有力途径。通过结合这两个概念，最近已建立了光氧化还原和镍双催化的级联反应，它们为获得一系列有价值的有机化合物提供了一种高效且温和的方法。
