Department of Parasitology, National Institute of Malariology, Parasitology and Entomology, Hanoi, Vietnam.
Department of Translational Physiology, Infectiology and Public Health, Ghent University, Ghent, Belgium.
Syst Rev. 2022 Jul 5;11(1):138. doi: 10.1186/s13643-022-02013-3.
Fascioliasis is an emerging public health threat in a number of regions worldwide, including Southeast Asia. Up to now, a summary of current knowledge on the occurrence and the distribution in Southeast Asia is lacking. We therefore aim to gather recent information on the distribution and prevalence of and the associated risk factors for Fasciola spp. infections in humans, animals, and plant carriers in Southeast Asia.
Bibliographic and gray literature databases as well as reference lists of important review articles will be searched for relevant records that are published between January 1, 2000, and the search date. The systematic review will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting systematic reviews. The primary outcomes will be both the prevalence of Fasciola spp. in the human and animal hosts, and on plant carriers in Southeast Asia, and the risk factors for occurrence of Fasciola spp. Secondary outcomes are the prevalence of Fasciola spp. in subpopulations (e.g., children and patients visiting clinics), the mapping of different diagnostic tests used, and the occurrence of the different Fasciola spp. in the study region. A descriptive statistical analysis will be conducted, and a meta-analysis will be run to estimate the prevalence of human and animal fascioliasis respectively, in Southeast Asia.
This systematic review will summarize the current knowledge on the epidemiology of Fasciola spp. infections in Southeast Asia.
This systematic review has been registered with the International Prospective Register of Systematic Reviews (PROSPERO), reference number: CRD42021261104 .
在世界范围内的多个地区，包括东南亚，片形吸虫病已成为新出现的公共卫生威胁。到目前为止，缺乏对东南亚发生情况和分布的综合认识。因此，我们旨在收集有关东南亚人类、动物和植物媒介中片形吸虫属感染的分布、流行情况和相关危险因素的最新信息。
将检索 2000 年 1 月 1 日至检索日期之间发表的相关记录，文献检索包括文献数据库和灰色文献数据库以及重要综述文章的参考文献列表。系统评价将根据系统评价和荟萃分析的首选报告项目（PRISMA）指南报告。主要结果将是东南亚人类和动物宿主以及植物媒介中片形吸虫属的流行率，以及片形吸虫属发生的危险因素。次要结果是亚人群（如儿童和就诊患者）中片形吸虫属的流行率、不同诊断试验的使用情况以及研究区域中不同的片形吸虫属的发生情况。将进行描述性统计分析，并进行荟萃分析，以分别估计东南亚人类和动物片形吸虫病的流行率。
本系统评价将总结东南亚片形吸虫属感染的流行病学现状。
本系统评价已在国际前瞻性系统评价登记册（PROSPERO）中注册，注册号：CRD42021261104。
