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急性肝衰竭:一种机制复杂的临床严重综合征。

Acute liver failure: A clinically severe syndrome characterized by intricate mechanisms.

作者信息

An Ran, Wang Jing-Lin

机构信息

Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Nanjing 210008, Jiangsu Province, China.

出版信息

World J Hepatol. 2024 Jul 27;16(7):1067-1069. doi: 10.4254/wjh.v16.i7.1067.

Abstract

Acute liver failure presents as a clinical syndrome characterized by swift deterioration and significant mortality rates. Its underlying mechanisms are intricate, involving intricate interplays between various cells. Given the current scarcity of treatment options, there's a pressing need to diligently uncover the disease's core mechanisms and administer targeted therapies accordingly.

摘要

急性肝衰竭表现为一种临床综合征,其特征是迅速恶化且死亡率很高。其潜在机制错综复杂,涉及各种细胞之间复杂的相互作用。鉴于目前治疗选择匮乏,迫切需要努力揭示该疾病的核心机制并据此进行靶向治疗。

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本文引用的文献

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Management of Acute Liver Failure: Update 2022.急性肝衰竭的管理:2022 年更新。
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Macrophage Polarization and Its Role in Liver Disease.巨噬细胞极化及其在肝脏疾病中的作用。
Front Immunol. 2021 Dec 14;12:803037. doi: 10.3389/fimmu.2021.803037. eCollection 2021.

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