Vitucci Daniela, Martone Domenico, Alfieri Andreina, Buono Pasqualina
Department of Movement Sciences and Wellbeing, University Parthenope, Naples, Italy.
CEINGE-Biotecnologie Avanzate Franco Salvatore, Naples, Italy.
Front Mol Med. 2023 Jun 6;3:1202190. doi: 10.3389/fmmed.2023.1202190. eCollection 2023.
There are a lot of evidences on the beneficial effects mediated by exercise on the prevention of not communicable diseases (NCDs) including different type of cancer. The production of circulating exerkines transported in exosomes represents a novel pathway activated by exercise. However, the biological mechanisms that could explain the role of exosomes in cancer prevention have been not fully elucidated. The aim of this mini-review is to provide an update on the biological mechanisms bringing the release of muscle-derived exosomes during exercise and cancer prevention.
有大量证据表明运动对预防包括不同类型癌症在内的非传染性疾病具有有益作用。运动激活的一条新途径是由外泌体转运的循环运动因子的产生。然而，能够解释外泌体在癌症预防中作用的生物学机制尚未完全阐明。本综述的目的是提供有关运动过程中肌肉衍生外泌体释放及癌症预防的生物学机制的最新信息。
