School of Chemistry and Chemical Engineering, Xianyang Normal University, Xian Yang 712000, China.
Emerald Experts laboratory, Isfahan Science and Technology Town, Isfahan 84156-83111, Iran.
Nanoscale Horiz. 2024 Sep 23;9(10):1703-1724. doi: 10.1039/d4nh00209a.
MXene-based architectures have paved the way in various fields, particularly in healthcare area, owing to their remarkable physiochemical and electromagnetic characteristics. Moreover, the modification of MXene structures and their combination with polymeric networks have gained considerable prominence to further develop their features. The combination of electrospun fibers with MXenes would be promising in this regard since electrospinning is a well-established technique that is now being directed toward commercial biomedical applications. The introduction of MXenes into electrospun fibrous frameworks has highlighted outcomes in various biomedical applications, including cancer therapy, controlled drug delivery, antimicrobial targets, sensors, and tissue engineering. Correspondingly, this review describes the employed strategies for the preparation of electrospun configurations in tandem with MXene nanostructures with remarkable characteristics. Next, the advantages of MXene-decorated electrospun fibers for use in biomedical applications are comprehensively discussed. According to the investigations, rich surface functional groups, hydrophilicity, large surface area, photothermal features, and antimicrobial and antibacterial activities of MXenes could synergize the performance of electrospun layers to engineer versatile biomedical targets. Moreover, the future of this path is clarified to combat the challenges related to the electrospun fibers decorated with MXene nanosheets.
基于 MXene 的架构因其显著的物理化学和电磁特性，在各个领域（特别是在医疗保健领域）开辟了道路。此外，对 MXene 结构的修饰及其与聚合物网络的结合，已经引起了相当大的关注，以进一步发展它们的特性。将电纺纤维与 MXenes 结合在这方面很有前景，因为电纺技术是一种成熟的技术，现在正朝着商业生物医学应用的方向发展。将 MXenes 引入电纺纤维框架中，在癌症治疗、控制药物释放、抗菌靶点、传感器和组织工程等各种生物医学应用中取得了显著的成果。相应地，本综述描述了制备与具有显著特性的 MXene 纳米结构相结合的电纺结构的所采用的策略。接下来，全面讨论了 MXene 修饰的电纺纤维在生物医学应用中的优势。根据研究，MXenes 丰富的表面官能团、亲水性、大的表面积、光热特性以及抗菌和抑菌活性，可以协同电纺层的性能，以工程化多功能生物医学靶标。此外，还阐明了这条道路的未来，以应对与 MXene 纳米片修饰的电纺纤维相关的挑战。
