坦桑尼亚艾滋病毒感染者对结核病预防性治疗的认知：一项在坦桑尼亚选定地区开展的横断面调查。

Knowledge of Tuberculosis preventive treatment among people living with HIV: A cross-sectional survey in selected regions of Tanzania.

作者信息

Alexander Felix Christopher, Mshiu Johnson Jeremia, Rushaigo Anelisa Martin, Mgina Erick Josephat, Wiketye Victor Enock, Mtundi Segere Chacha, Haule Sylvia Thomas, Katende Michael Kipenda, Evarist Esther Manka, Kapama Luciana Charles, Shemdoe Aloisia Ibrahim, Makasi Charles Elias, Lolakeha Majaha Melkisedeck, Minja Victor Kenedy, Kimbute Omary Abdallah, Stephen Kunda John, Range Nyagosya Segere, Maokola Werner Meinrad, Ngowi Bernard James, Nyigo Vitus Alberto, Kilale Andrew Martin

机构信息

National Institute for Medical Research-Muhimbili Center, Dar es Salaam, Tanzania.

National Institute for Medical Research headquarter, Dar es Salaam, Tanzania.

出版信息

PLoS One. 2024 Aug 1;19(8):e0307670. doi: 10.1371/journal.pone.0307670. eCollection 2024.

DOI:10.1371/journal.pone.0307670

PMID:39088461

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11293724/

Abstract

BACKGROUND

Tuberculosis remains a significant global health concern, especially for People Living with HIV, who are at an increased risk of severe TB disease. Despite the availability of TB Preventive Treatment, knowledge gaps persist among People Living with HIV regarding its importance, accessibility, and administration. The study aimed to assess TPT knowledge levels and determinants among People Living with HIV in Tanzania.

METHODS

A cross-sectional survey was conducted from April to May 2023 in 12 regions of mainland Tanzania. The study included PLHIV aged 18 years and above, receiving HIV care in selected Care and Treatment Centers. Data were collected through face-to-face interviews using a semi-structured questionnaire covering sociodemographic characteristics and Tuberculosis preventive treatment knowledge. Descriptive statistics, chi-square tests, and logistic regression analyses were employed for data analysis.

RESULTS

Out of the 391 People Living with HIV interviewed, 71.4% demonstrated adequate Tuberculosis preventive treatment knowledge. Female participants, those attending urban health facilities, and individuals with longer durations of HIV care exhibited higher Tuberculosis preventive treatment knowledge levels. However, knowledge disparities persisted based on demographic characteristics such as gender and location of health facilities.

CONCLUSION

While a considerable portion of People Living with HIV demonstrated adequate higher Tuberculosis preventive treatment knowledge, addressing gaps among those with lower understanding is crucial. Targeted education campaigns tailored to the needs of People Living with HIV, especially in rural areas and among male populations, are essential. Collaborative efforts between national health programs and community organizations are vital to integrate Tuberculosis preventive treatment awareness effectively into comprehensive HIV care programs, ultimately reducing the burden of Tuberculosis among People Living with HIV and the general population.

摘要

背景

结核病仍然是一个重大的全球卫生问题，尤其是对于感染艾滋病毒的人来说，他们患严重结核病的风险更高。尽管有结核病预防性治疗，但感染艾滋病毒的人在其重要性、可及性和管理方面仍然存在知识差距。该研究旨在评估坦桑尼亚感染艾滋病毒的人的结核病预防性治疗知识水平及其决定因素。

方法

2023年4月至5月在坦桑尼亚大陆的12个地区进行了一项横断面调查。该研究纳入了年龄在18岁及以上、在选定的护理和治疗中心接受艾滋病毒护理的艾滋病毒感染者。通过面对面访谈收集数据，使用一份涵盖社会人口学特征和结核病预防性治疗知识的半结构化问卷。采用描述性统计、卡方检验和逻辑回归分析进行数据分析。

结果

在接受访谈的391名艾滋病毒感染者中，71.4%表现出足够的结核病预防性治疗知识。女性参与者、在城市卫生设施就诊的人以及接受艾滋病毒护理时间较长的人表现出较高的结核病预防性治疗知识水平。然而，基于性别和卫生设施位置等人口统计学特征的知识差距仍然存在。

结论

虽然相当一部分艾滋病毒感染者表现出足够高的结核病预防性治疗知识，但解决理解较低者之间的差距至关重要。针对艾滋病毒感染者的需求，特别是在农村地区和男性人群中开展有针对性的教育活动至关重要。国家卫生项目和社区组织之间的合作努力对于将结核病预防性治疗意识有效纳入全面的艾滋病毒护理项目至关重要，最终减轻艾滋病毒感染者和普通人群中的结核病负担。