• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

埃塞俄比亚亚的斯亚贝巴的艾滋病毒感染者中异烟肼预防性治疗的提供和知晓情况。

Provision and awareness for isoniazid preventive therapy among PLHIV in Addis Ababa, Ethiopia.

机构信息

School of Public Health, Medical Faculty, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

BMC Int Health Hum Rights. 2012 Mar 27;12:2. doi: 10.1186/1472-698X-12-2.

DOI:10.1186/1472-698X-12-2
PMID:22452967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3353253/
Abstract

BACKGROUND

The risk of acquiring tuberculosis by People living with HIV (PLHIV) could significantly be reduced through provision of isoniazid preventive therapy (IPT). In Ethiopia, it is neither practiced well nor researched in depth. Our objective was to assess IPT provision and awareness among PLHIV in Addis Ababa City Administration.

METHODS

Between February 2008 and May 2008, a cross sectional facility-based survey was conducted by exit interview of 406 PLHIV from six health facilities. The findings were analyzed and described in this report.

RESULTS

The proportion of PLHIV ever had been provided with IPT were 74 of 231 TB free PLHIV (32.0%) and the proportion of having information about IPT among study participants was 29.8%. Females were about two times more informed about the provision of IPT in their health facilities than males [AOR (95%CI): 2.18 (1.31-3.61)].

CONCLUSIONS

We conclude that the practice of provision of IPT for PLHIV is high, but there is room for improvement. Provision of INH for TB free PLHIV has to be strengthened with better diagnostic facilities to certainly rule out active TB cases.

摘要

背景

通过提供异烟肼预防性治疗(IPT),可以显著降低艾滋病毒感染者(PLHIV)感染结核病的风险。在埃塞俄比亚,IPT 既没有得到很好的实施,也没有进行深入的研究。我们的目的是评估亚的斯亚贝巴市行政当局中 PLHIV 对 IPT 的提供和认识情况。

方法

2008 年 2 月至 5 月期间,通过对来自六个卫生机构的 406 名 PLHIV 进行出院访谈,进行了一项横断面的基于机构的调查。本报告分析和描述了调查结果。

结果

在 231 名无结核病的 PLHIV 中,有 74 人曾接受过 IPT,研究参与者中对 IPT 有了解的比例为 29.8%。与男性相比,女性在卫生机构中接受 IPT 提供信息的比例高出两倍[比值比(95%置信区间):2.18(1.31-3.61)]。

结论

我们的结论是,为 PLHIV 提供 IPT 的做法很高,但仍有改进的空间。必须加强对无结核病 PLHIV 提供 INH 的措施,并提供更好的诊断设施,以确定排除活动性结核病病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ec/3353253/3da951a5c63c/1472-698X-12-2-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ec/3353253/3da951a5c63c/1472-698X-12-2-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75ec/3353253/3da951a5c63c/1472-698X-12-2-1.jpg

相似文献

1
Provision and awareness for isoniazid preventive therapy among PLHIV in Addis Ababa, Ethiopia.埃塞俄比亚亚的斯亚贝巴的艾滋病毒感染者中异烟肼预防性治疗的提供和知晓情况。
BMC Int Health Hum Rights. 2012 Mar 27;12:2. doi: 10.1186/1472-698X-12-2.
2
Tuberculosis case finding and isoniazid preventive therapy among people living with HIV at public health facilities of Addis Ababa, Ethiopia: a cross-sectional facility based study.埃塞俄比亚亚的斯亚贝巴公共卫生设施中艾滋病毒感染者的结核病病例发现及异烟肼预防性治疗:一项基于机构的横断面研究。
BMC Public Health. 2014 Jan 18;14:52. doi: 10.1186/1471-2458-14-52.
3
Tuberculosis preventive treatment uptake among people living with HIV during COVID-19 period in Addis Ababa, Ethiopia: a retrospective data review.在 COVID-19 期间,埃塞俄比亚亚的斯亚贝巴的艾滋病毒感染者中结核病预防治疗的接受情况:一项回顾性数据分析。
BMC Infect Dis. 2024 May 17;24(1):499. doi: 10.1186/s12879-024-09403-z.
4
Effectiveness of isoniazid preventative therapy in reducing incidence of active tuberculosis among people living with HIV/AIDS in public health facilities of Addis Ababa, Ethiopia: a historical cohort study.异烟肼预防性治疗对降低埃塞俄比亚亚的斯亚贝巴公共卫生设施中艾滋病毒/艾滋病感染者活动性结核病发病率的有效性:一项历史性队列研究。
BMC Infect Dis. 2017 Jan 3;17(1):5. doi: 10.1186/s12879-016-2109-7.
5
Intensified tuberculosis case finding, implementation of isoniazid preventive therapy and associated factors among people living with human immunodeficiency virus at public health facilities of Harari Region, Eastern Ethiopia: A cross-sectional study.埃塞俄比亚东部哈拉里地区公共卫生机构中人类免疫缺陷病毒感染者的强化结核病病例发现、异烟肼预防性治疗的实施及相关因素:一项横断面研究
Int J Health Sci (Qassim). 2017 Jan-Mar;11(1):1-8.
6
Outcomes of isoniazid preventive therapy among people living with HIV in Kenya: A retrospective study of routine health care data.肯尼亚艾滋病毒感染者中异烟肼预防性治疗的结局:基于常规医疗保健数据的回顾性研究。
PLoS One. 2020 Dec 2;15(12):e0234588. doi: 10.1371/journal.pone.0234588. eCollection 2020.
7
A prospective cohort study of outcomes for isoniazid prevention therapy: a nested study from a national QI collaborative in Uganda.异烟肼预防性治疗结局的前瞻性队列研究:乌干达一项全国性质量改进协作项目中的嵌套研究
AIDS Res Ther. 2020 May 27;17(1):28. doi: 10.1186/s12981-020-00285-0.
8
Use of isoniazid preventive therapy for tuberculosis prophylaxis among people living with HIV/AIDS: a review of the literature.在艾滋病毒/艾滋病感染者中使用异烟肼预防性治疗预防结核病:文献综述
J Acquir Immune Defic Syndr. 2015 Apr 15;68 Suppl 3(Suppl 3):S297-305. doi: 10.1097/QAI.0000000000000497.
9
Factors associated with isoniazid preventive treatment interruption and completion among PLHIV in Gombe Hospital, Uganda, 2017-2019.2017 - 2019年乌干达贡贝医院艾滋病毒感染者中与异烟肼预防性治疗中断和完成相关的因素
J Clin Tuberc Other Mycobact Dis. 2023 Jan 24;31:100349. doi: 10.1016/j.jctube.2023.100349. eCollection 2023 May.
10
Early-phase scale-up of isoniazid preventive therapy for people living with HIV in two districts in Malawi (2017).在马拉维的两个地区对艾滋病毒感染者进行早期扩大异烟肼预防性治疗(2017 年)。
PLoS One. 2021 Apr 1;16(4):e0248115. doi: 10.1371/journal.pone.0248115. eCollection 2021.

引用本文的文献

1
Knowledge of Tuberculosis preventive treatment among people living with HIV: A cross-sectional survey in selected regions of Tanzania.坦桑尼亚艾滋病毒感染者对结核病预防性治疗的认知:一项在坦桑尼亚选定地区开展的横断面调查。
PLoS One. 2024 Aug 1;19(8):e0307670. doi: 10.1371/journal.pone.0307670. eCollection 2024.
2
Health workers' knowledge and practice of Isoniazid preventive treatment guidelines in health facilities in Ebonyi State, Nigeria.尼日利亚埃邦伊州卫生机构中卫生工作者对异烟肼预防治疗指南的知识和实践。
Malawi Med J. 2022 Sep;34(3):184-191. doi: 10.4314/mmj.v34i3.7.
3
Effect of mobile-phone messaging on patient and health-worker knowledge and adherence to the isoniazid preventive therapy guideline in HIV clinics in Southeast, Nigeria.

本文引用的文献

1
Adherence with isoniazid for prevention of tuberculosis among HIV-infected adults in South Africa.南非艾滋病毒感染成人中异烟肼预防结核病的依从性。
BMC Infect Dis. 2006 Jun 13;6:97. doi: 10.1186/1471-2334-6-97.
2
Adherence to TB preventive therapy for HIV-positive patients in rural South Africa: implications for antiretroviral delivery in resource-poor settings?南非农村地区艾滋病毒呈阳性患者对结核病预防性治疗的依从性:对资源匮乏地区抗逆转录病毒治疗的影响?
Int J Tuberc Lung Dis. 2005 Mar;9(3):263-9.
3
Knowledge of tuberculosis and associated health-seeking behaviour among rural Vietnamese adults with a cough for at least three weeks.
尼日利亚东南部艾滋病诊所中手机短信对患者和卫生工作者对异烟肼预防治疗指南的知识和依从性的影响。
BMC Infect Dis. 2021 Oct 19;21(1):1080. doi: 10.1186/s12879-021-06759-4.
4
Knowledge and adherence to isoniazid preventive therapy among people living with HIV in multilevel health facilities in South-East, Nigeria: baseline findings from a quasi-experimental study.在尼日利亚东南部的多层次卫生机构中,艾滋病毒感染者对异烟肼预防性治疗的认知和坚持情况:一项准实验研究的基线结果。
Pan Afr Med J. 2020 Aug 10;36:261. doi: 10.11604/pamj.2020.36.261.22496. eCollection 2020.
5
Utilization of isoniazid prophylaxis therapy and its associated factors among HIV positive clients taking antiretroviral therapy at Fre Semaetat primary hospital, Hawzien districts, Tigrai, Northern Ethiopia.埃塞俄比亚北部提格雷州哈维恩地区弗雷塞马埃塔特初级医院接受抗逆转录病毒治疗的HIV阳性患者中异烟肼预防性治疗的使用情况及其相关因素。
Trop Dis Travel Med Vaccines. 2020 Jun 17;6:11. doi: 10.1186/s40794-020-00106-2. eCollection 2020.
6
Inequality in uptake of isoniazid prevention therapy and Mantoux test among pregnant women with HIV in the Eastern Cape, South Africa.南非东开普省 HIV 感染孕妇中异烟肼预防治疗和曼托试验接受情况的不平等。
BMC Public Health. 2019 Oct 29;19(1):1407. doi: 10.1186/s12889-019-7769-y.
7
Assessment of national tuberculosis and HIV collaborative program implementation status in health care settings of Ethiopia.埃塞俄比亚医疗机构中全国结核病与艾滋病合作项目实施状况评估
Ethiop J Public Health Nutr. 2017;1(2):93-98.
8
Barriers in the implementation of isoniazid preventive therapy for people living with HIV in Northern Ethiopia: a mixed quantitative and qualitative study.埃塞俄比亚北部为艾滋病毒感染者实施异烟肼预防性治疗的障碍:一项定量与定性相结合的研究
BMC Public Health. 2016 Aug 19;16(1):840. doi: 10.1186/s12889-016-3525-8.
越南农村地区咳嗽至少三周的成年人对结核病的了解及相关就医行为
Scand J Public Health Suppl. 2003;62:59-65. doi: 10.1080/14034950310015121.
4
Efficacy of secondary isoniazid preventive therapy among HIV-infected Southern Africans: time to change policy?南非艾滋病毒感染者中异烟肼二级预防性治疗的疗效:是时候改变政策了吗?
AIDS. 2003 Sep 26;17(14):2063-70. doi: 10.1097/00002030-200309260-00007.
5
Effect of post-treatment isoniazid on prevention of recurrent tuberculosis in HIV-1-infected individuals: a randomised trial.治疗后使用异烟肼对预防HIV-1感染者复发性结核病的作用:一项随机试验。
Lancet. 2000 Oct 28;356(9240):1470-4. doi: 10.1016/S0140-6736(00)02870-1.
6
Drugs for preventing tuberculosis in HIV infected persons.用于预防HIV感染者患结核病的药物。
Cochrane Database Syst Rev. 2000(2):CD000171. doi: 10.1002/14651858.CD000171.
7
Twice weekly tuberculosis preventive therapy in HIV infection in Zambia.赞比亚针对HIV感染的每周两次结核病预防性治疗
AIDS. 1998 Dec 24;12(18):2447-57. doi: 10.1097/00002030-199818000-00014.
8
Effect of isoniazid prophylaxis on incidence of active tuberculosis among Thai HIV-infected individuals.异烟肼预防性治疗对泰国HIV感染者活动性结核病发病率的影响。
J Med Assoc Thai. 1996 May;79(5):285-7.
9
Effect of isoniazid prophylaxis on incidence of active tuberculosis and progression of HIV infection.异烟肼预防性治疗对活动性肺结核发病率及HIV感染进展的影响。
Lancet. 1993 Jul 31;342(8866):268-72. doi: 10.1016/0140-6736(93)91817-6.