Department of Community Medicine, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.
Department of Community Medicine, Ebonyi State University, Abakaliki, Ebonyi State, Nigeria.
Pan Afr Med J. 2020 Aug 10;36:261. doi: 10.11604/pamj.2020.36.261.22496. eCollection 2020.
isoniazid preventive therapy is a crucial component of TB/HIV collaborative program and patient good knowledge and adherence to this preventive treatment are essential in improving implementation. The aim of this study was to determine the knowledge and adherence to isoniazid preventive therapy among patients receiving HIV care.
this is a baseline result of a quasi-experimental study which was carried out among 200 patients receiving HIV care in six high patient load health facilities providing comprehensive HIV care in Ebonyi State. This included a tertiary health facility and five secondary level health facilities. We used structured interviewer-administered questionnaire to collect information from the participants. Adherence was assessed by self-reports. Descriptive, bivariate and multivariate logistic regression analyses were conducted using SPSS version 20 at 5% level of significance.
majority (65%) of the respondents were between 30 and 49 years and most (73.5%) were females. Majority (85%) had been on antiretroviral therapy (ART) for more than one year. More than half of the respondents had ever received and had been counselled on IPT (55%, 62% respectively) while only 17.5% were on IPT during the study. More than half (60.5%) of the respondents had low level of knowledge. Marital status was the only predictor of knowledge. Unmarried respondents were 2 times more likely to have knowledge of IPT compared with the married (AOR = 2.11, CI = 1.10-4.06). Among the 35 patients who were on IPT, 32 (91%) reported good adherence in the 30 days preceding the survey. there was poor knowledge of IPT among the respondents however self-reported adherence was high. We recommend intensification of general and personalized education of PLHIV on IPT by health workers.
异烟肼预防治疗是结核病/艾滋病合作项目的重要组成部分，患者对这种预防治疗的良好了解和坚持是提高实施效果的关键。本研究旨在确定接受艾滋病护理的患者对异烟肼预防治疗的了解程度和坚持情况。
这是一项准实验研究的基线结果，该研究在埃邦伊州 6 个高患者负荷的卫生机构中接受艾滋病毒护理的 200 名患者中进行，其中包括一个三级卫生机构和五个二级卫生机构。我们使用结构式访谈者管理问卷从参与者那里收集信息。通过自我报告评估依从性。使用 SPSS 版本 20 在 5%的显著性水平下进行描述性、双变量和多变量逻辑回归分析。
大多数（65%）受访者年龄在 30 至 49 岁之间，大多数（73.5%）为女性。大多数（85%）接受抗逆转录病毒治疗（ART）已超过一年。超过一半的受访者曾接受过并接受过 IPT 咨询（55%、62%），而在研究期间只有 17.5%的人接受了 IPT。超过一半（60.5%）的受访者知识水平较低。婚姻状况是知识的唯一预测因素。与已婚者相比，未婚者对 IPT 的了解更有可能增加两倍（AOR=2.11，CI=1.10-4.06）。在 35 名接受 IPT 的患者中，32 名（91%）在调查前 30 天报告了良好的依从性。然而，受访者对 IPT 的知识水平较低，但自我报告的依从性较高。我们建议卫生工作者加强对 PLHIV 的一般和个性化 IPT 教育。
